Trial reportScientific reports2026
Desflurane versus sevoflurane and postoperative inflammatory biomarkers in older adults undergoing minor- to moderate-risk noncardiac surgery.
Trial report in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Volatile anesthetics modulate inflammatory responses, but it remains unclear whether desflurane and sevoflurane differ in their effects on postoperative inflammation. We evaluated in this secondary analysis of a prospective randomized trial, the effect of desflurane versus sevoflurane anesthesia on postoperative inflammatory biomarkers in older adults undergoing minor- to moderate-risk noncardiac surgery. We included all 190 patients who were enrolled in the main trial in this analysis. We administered desflurane or sevoflurane, aiming for a BIS value of 50 ± 5. C-reactive protein, Interleukin-6, and Procalcitonin concentrations were measured preoperatively, within one hour after surgery, and on the second postoperative day. We observed no significant difference in maximum postoperative Interleukin-6 (8.11 pg ml
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