ArticleMacromolecular rapid communications2026
Investigation of PSBMA-PU Ternary Copolymer-Based Semipermeable Membrane for Macro-Encapsulation of Cells.
Article in Macromolecular rapid communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Cell macro-encapsulation necessitates semi-permeable membrane materials with strong resistance to fibrotic encapsulation in vivo. In this study, segmented polyzwitterionic-polyurethane block copolymers (SPU) were synthesized to meet this requirement. Fourier-transform infrared and X-ray photoelectron spectroscopy confirmed the molecular structure of the successfully synthesized SPU. When incorporated into commercial polyurethane, SPU significantly reduced the hydrophilicity of electrospun fiber membranes and exhibited minimal protein adsorption. The resulting membranes demonstrated favorable mechanical properties, well-defined porous architecture, and efficient transmembrane mass transfer. Encapsulation experiments using BMSCs confirmed that the membrane effectively retained cells while supporting normal cellular growth, allowing secreted factors to diffuse through the membrane and induce M1-to-M2 macrophage polarization. In vivo subcutaneous implantation in rats showed that membranes containing the zwitterionic block copolymer elicited significantly thinner fibrous capsules than both unmodified polyurethane and PTFE controls at 14 and 28 days, with no signs of acute or chronic inflammation.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.