ArticleACS applied materials & interfaces2026
Cuttlefish Ink-Derived Melanin Nanoparticles Enabling NIR-Responsive Electrospun Nanofibrous Mats for On-Demand Selective Antibacterial Disinfection of Orthodontic Braces.
Article in ACS applied materials & interfaces, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Fixed orthodontic appliances facilitate bacterial accumulation on brackets and wires, increasing the risk of enamel demineralization and periodontal inflammation. To address this challenge, near-infrared (NIR) responsive nanofibrous mats were developed for on-demand antibacterial disinfection of orthodontic brackets by incorporating cuttlefish ink-derived melanin nanoparticles (MNPs) into a poly(vinyl alcohol)/poly(ethylene oxide) (PVA/PEO) matrix. The incorporation of MNPs improved physicochemical properties, including enhanced thermal stability (∼77 °C increase in decomposition temperature), increased swelling capacity (∼2-fold compared with melanin-free fibers), and improved wettability. After thermal cross-linking, the fibrous network remained structurally stable in aqueous conditions with morphology preserved for up to 1 month and low melanin loss. Strong antioxidant performance was observed, reaching ∼60% 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical-scavenging after 10 h.
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