ReviewZhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences2026
[Research progress on the roles of mitochondrial fusion, fission, and mitophagy in burn wound healing].
Review in Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mitochondria, known as the "energy factory" of cells, play a critical role in burn wound healing owing to their structural and functional stability. Following burn injury, mitochondrial damage exacerbates inflammatory responses, triggers endogenous apoptotic pathways, and reduces adenosine triphosphate synthesis, thereby delaying tissue repair. The dynamic balance between mitochondrial fusion and fission, together with mitophagy, is a key regulatory mechanism that maintains mitochondrial structural integrity and functional stability. Moderate mitochondrial fission promotes wound healing, whereas excessive fission induces overproduction of reactive oxygen species and inflammatory cytokines, which is detrimental to repair. Mitochondrial fusion may confer benefits to wound healing, and mitophagy alleviates apoptosis and oxidative stress, thereby regulating multiple stages of burn wound healing. This review focuses on the maintenance of the mitochondrial fusion-fission balance and mitophagy, elaborates their specific roles in burn wound repair, and discusses the clinical prospects of targeting these mechanisms for the prevention and treatment of post-burn injuries.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.