ArticleUltrasonography (Seoul, Korea)2026
Association of triglyceride-driven residual atherosclerotic risk with carotid stiffening assessed using ultrafast ultrasound imaging in individuals with hypertriglyceridemia.
Article in Ultrasonography (Seoul, Korea), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
purposePatients with hypertriglyceridemia retain residual atherosclerotic risk despite achieving low-density lipoprotein cholesterol (LDL-C) targets. This study investigated the association of this risk with carotid stiffening assessed by ultrafast pulse wave velocity (ufPWV).
methodsThis study included 518 participants who underwent simultaneous ufPWV and carotid intima-media thickness (cIMT) measurements. Participants were stratified by triglyceride (TG) level into TG-optimal, TG-normal, and TG-high groups. Pulse wave velocity (PWV) at the beginning of systole and at the end of systole (PWV-ES) were measured using ufPWV. Participants were also categorized by Framingham risk score (FRS) into low-, intermediate-, and high-risk subgroups and by LDL-C level into normal and high subgroups. Logistic regression analysis was used to evaluate the potential predictive role of increased PWV-ES.
resultsIn the total population and the normal LDL-C subgroup, both the TG-high and TG-normal groups had higher PWV-ES and cIMT values than the TG-optimal group (all P<0.05). Among participants with normal cIMT (<0.050 cm), PWV-ES effectively differentiated the TG-optimal and TG-high groups (P<0.001), but this difference was not observed when cIMT was ≥0.050 cm. Similarly, PWV-ES differentiated TG groups within the low-risk FRS subgroup (all P<0.01), but not within the intermediate- or high-risk subgroups. Logistic regression showed that increased PWV-ES was independently associated with high TG levels in both the normal LDL-C subgroup (odds ratio [OR], 1.21; P=0.006) and the high LDL-C subgroup (OR, 1.57; P=0.023) after adjustment for LDL-C alone.
conclusionufPWV-quantified carotid stiffness is associated with elevated TG-driven residual atherosclerotic risk, independent of LDL-C.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.