ArticleFrontiers in medicine2026
Obinutuzumab for refractory minimal change disease in obese patients: a case series.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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5 authors.
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Abstract
Minimal change disease (MCD) is a common cause of nephrotic syndrome in adults. Rituximab, a type I anti-CD20 antibody, is effective in many cases, but up to 40% of patients show an insufficient or transient response. Obesity, a frequent comorbidity, is associated with chronic low-grade inflammation and B-cell dysfunction, which may contribute to suboptimal treatment outcomes. Obinutuzumab, a type II anti-CD20 antibody, induces more profound B-cell depletion than rituximab. We report two obese patients (BMI 32.10 and 42.45 kg/m
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