Evidence map›Paper›PMID 42222028›Full record

ReviewClinical neurophysiology practice2026

Brain perfusion imaging in patients with status epilepticus, seizures, and IIC patterns.

Khalil S Husari, Michael Porambo, Vivek S Yedavalli, Peter W Kaplan

Abstract readReview
In one paragraph

Review in Clinical neurophysiology practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Khalil S HusariEpilepsy Center, Department of Neurology, Johns Hopkins University, Baltimore, MD 21287, USA.
Michael PoramboDivision of Neuroradiology, The Johns Hopkins Hospital, Baltimore, MD 21287, USA.
Vivek S YedavalliDivision of Neuroradiology, The Johns Hopkins Hospital, Baltimore, MD 21287, USA.
Peter W KaplanDepartment of Neurology, Johns Hopkins Bayview Medical Center, Baltimore, MD 21224, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over the past decade, Computed Tomography perfusion (CTP) and Magnetic Resonance Perfusion (MRP) imaging have become increasingly valuable tools in the assessment of acute neurological emergencies, including stroke and stroke mimics. These modalities can demonstrate seizure-related alterations in regional cerebral blood flow across the spectrum of epileptic conditions. While ictal states classically manifest as regional hyperperfusion and interictal periods typically show hypoperfusion or normal perfusion, the perfusion patterns are more nuanced and influenced by several variables. This review examines the current literature on CTP and MRP applications in status epilepticus, seizures, and ictal-interictal continuum patterns, with particular emphasis on the comparative diagnostic accuracy across different clinical scenarios and imaging techniques.

Indexed as

CTPIICLPDsMRIMR perfusionPerfusion

Identifiers

PMID42222028
PMCPMC13217417

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.