SynthesisFrontiers in neurology
Effectiveness of transcutaneous auricular vagus nerve stimulation in stroke rehabilitation: a systematic review and meta-analysis of randomized clinical trials.
Synthesis in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
- Erratum issued
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and aim: Transcutaneous auricular vagus nerve stimulation (taVNS) has demonstrated potential efficacy in post-stroke functional recovery. This study aimed to systematically synthesize data evaluating the effects of taVNS in terms of improving motor function, mental health, and activities of daily living (ADL) in patients experiencing stroke following intervention. Methods: Electronic databases including EMBASE, Cochrane Library, PubMed, Web of Science, China National Knowledge Infrastructure, Wanfang, and VIP were searched from their inception to September 2025. All randomized controlled trials that applied taVNS to patients experiencing stroke were included. Results: Ten randomized controlled trials (RCTs) involving 512 patients were included in the analysis. The results showed that compared with the control group, the taVNS group demonstrated significantly increased motor function scores [standardized mean difference (SMD) = 1.21; 95% CI: 0.88-1.55; Conclusion: taVNS improves motor function, mental health, and ADL outcomes in patients experiencing stroke. The combination of taVNS stimulation frequency, current intensity, and intervention duration constitutes a key modulator influencing treatment efficacy. Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/view/CRD42025633212, identifier PROSPERO (CRD42025633212).
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.