Evidence map›Paper›PMID 42222744›Full record

ArticlePNAS nexus2026

Oncogenic PIK3CA mutations shape an immunoregulatory microenvironment in mosaic overgrowth disorders.

Ilaria Galasso, Charles Bayard, Camille Blériot, Sophia Ladraa, Wan Ting Kong, Rubina Cassaca, Clément Hoguin, Sanela Protic, Jérôme Megret, Nicolas Goudin and 10 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PNAS nexus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Ilaria GalassoUniversité Paris Cité, 75006 Paris, France.
Charles BayardUniversité Paris Cité, 75006 Paris, France.
Camille BlériotInstitut National de la Santé et de la Recherche Médicale U1151, Institut Necker-Enfants Malades, 149 rue de Sèvres, 75015 Paris, France.ORCID https://orcid.org/0000-0002-4298-2888
Sophia LadraaUniversité Paris Cité, 75006 Paris, France.
Wan Ting KongINSERM U1015, Gustave Roussy Cancer Campus, 94085 Villejuif, France.ORCID https://orcid.org/0000-0002-9271-841X
Rubina CassacaUniversité Paris Cité, 75006 Paris, France.ORCID https://orcid.org/0000-0002-7250-4414
Clément HoguinUniversité Paris Cité, 75006 Paris, France.ORCID https://orcid.org/0000-0002-2783-676X
Sanela ProticUniversité Paris Cité, 75006 Paris, France.
Jérôme MegretStructure Fédérative de Recherche Necker, INSERM US24, CNRS UAR 3633, Institut Necker-Enfants Malades, 75015 Paris, France.
Nicolas GoudinNecker Bio-Image Analysis, INSERM US24/CNRS UMS 3633, 75015 Paris, France.ORCID https://orcid.org/0000-0002-3967-4016
Nicolas SignolleBiopathology Department, Gustave Roussy Cancer Campus, 94085 Villejuif, France.
Jean-Yves ScoazecDépartement de Biologie et Pathologie Médicale, Gustave Roussy Cancer Campus, 94085 Villejuif, France.
Ivan NemazanyyPlatform for Metabolic Analyses, Structure Fédérative de Recherche Necker, INSERM US24, CNRS UAR 3633, Institut Necker-Enfants Malades, 94085 Paris, France.ORCID https://orcid.org/0000-0001-8080-839X
Estelle BalducciLaboratoire d'oncologie Hématologie, Hôpital Necker-Enfants Malades, AP-HP, 75015 Paris, France.
Patrick VillareseLaboratoire d'oncologie Hématologie, Hôpital Necker-Enfants Malades, AP-HP, 75015 Paris, France.ORCID https://orcid.org/0000-0003-1625-3785
Vahid AsnafiUniversité Paris Cité, 75006 Paris, France.
Sylvie FraitagService d'Anatomie Pathologique, Hôpital Necker-Enfants Malades, AP-HP, 75015 Paris, France.
Nicolas VenteclefInstitut National de la Santé et de la Recherche Médicale U1151, Institut Necker-Enfants Malades, 149 rue de Sèvres, 75015 Paris, France.ORCID https://orcid.org/0000-0002-6313-1214
Florent GinhouxINSERM U1015, Gustave Roussy Cancer Campus, 94085 Villejuif, France.ORCID https://orcid.org/0000-0002-2857-7755
Guillaume CanaudUniversité Paris Cité, 75006 Paris, France.ORCID https://orcid.org/0000-0002-9901-8635

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

macrophages immune cell responsePIK3CA-related overgrowth syndromeWarburg like Tumor microenvironment

Identifiers

PMID42222744
PMCPMC13222027

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.