Evidence map›Paper›PMID 42223268›Full record

ArticlemSphere2026

The bromodomain protein Bdf3 is sufficient to activate expression of a procyclin gene in bloodstream stage African trypanosomes.

Evan J Kim, Ethan L Goroza, Ashley Y Tan, Jolyne J Lin, Kieran C Saucedo, Fuminori Tanizawa, Jaclyn E Smith, Danae Schulz

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mSphere, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Evan J KimDepartment of Biology, Harvey Mudd College, Claremont, California, USA.
Ethan L GorozaDepartment of Biology, Harvey Mudd College, Claremont, California, USA.
Ashley Y TanDepartment of Biology, Harvey Mudd College, Claremont, California, USA.
Jolyne J LinDepartment of Biology, Harvey Mudd College, Claremont, California, USA.
Kieran C SaucedoDepartment of Biology, Harvey Mudd College, Claremont, California, USA.
Fuminori TanizawaDepartment of Biology, Harvey Mudd College, Claremont, California, USA.
Jaclyn E SmithInstitute for Genome Sciences, University of Maryland, Baltimore, Maryland, USA.
Danae SchulzDepartment of Biology, Harvey Mudd College, Claremont, California, USA.ORCID 0000-0002-0392-7245

Funding

National Science Foundation (NSF) CAREER 2041395
6 · The paper itself

Abstract

The early-branching eukaryotic parasite, IMPORTANCE: The

Indexed as

Gene Expression RegulationProtozoan ProteinsTrypanosoma brucei bruceiAnimalsMembrane GlycoproteinsPromoter Regions, GeneticVariant Surface Glycoproteins, TrypanosomaGPEET protein, Trypanosoma bruceiMembrane GlycoproteinsProtozoan ProteinsVariant Surface Glycoproteins, Trypanosomabromodomain proteinchromatinepigeneticsmolecular parasitologyTrypanosoma brucei

Identifiers

PMID42223268
PMCPMC13317214

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.