Evidence map›Paper›PMID 42223653›Full record

ArticleSocial psychiatry and psychiatric epidemiology2026

Bidirectional associations between insomnia symptoms and depression: a prospective cohort study.

Shuomin Wang, Mengting Dai, Qianyuan Li, Tianxue Hou, Shanshan Wang, Michael V Vitiello, Christina E Miyawaki, Minhui Liu

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Article in Social psychiatry and psychiatric epidemiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Shuomin Wang *School of Nursing, The University of Hong Kong, Hong Kong, China.
Mengting Dai *School of Nursing, Ningxia Medical University, No.1160 Shengli South Street, Xingqing District, Yinchuan, 750003, China.
Qianyuan LiDepartment of Geriatrics, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China.
Tianxue HouSchool of Nursing, The University of Hong Kong, Hong Kong, China.
Shanshan WangSchool of Nursing, The Hong Kong Polytechnic University, Hong Kong, China.
Michael V VitielloDepartment of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA.
Christina E MiyawakiGraduate College of Social Work, University of Houston, Houston, TX, USA.
Minhui LiuSchool of Nursing, Ningxia Medical University, No.1160 Shengli South Street, Xingqing District, Yinchuan, 750003, China. mliu62@jhu.edu.

Funding

Changsha Science and Technology Program Soft Science Project kh2302038Key R&D Program Project of Hunan Province Grant 2023SK2009Ministry of Education of Humanities and Social Science project 24YJA840009
6 · The paper itself

Abstract

purposeDepression and insomnia are both prevalent in older adults and exhibit a bidirectional relationship. Difficulty initiating sleep (DIS) and difficulty maintaining sleep (DMS) are major symptoms of insomnia. However, whether and how these two insomnia symptoms differ in their associations with depression among older adults is unknown. We aimed to investigate the association between insomnia symptoms (DIS and DMS) and depressive symptoms among older adults.

methodsWe used data of the 3,377 community-dwelling older adults from five waves (2011-2015) of the National Health and Aging Trends Study, a nationally representative survey of Medicare Beneficiaries in the United States. Depressive symptoms were assessed by the Patient Health Questionnaire-2. Insomnia symptoms included self-reports of DIS and DMS. Generalized estimating equation models were used to examine the concurrent and lagged associations between insomnia symptoms and depressive symptoms.

resultsParticipants were on average 76.0 ± 7.1 years old, predominantly female (59.2%), and non-Hispanic white (72.1%). Both DIS and DMS were concurrently associated with depressive symptoms. Longitudinally, DIS predicted subsequent depressive symptoms even after full adjustment, whereas DMS did not. Conversely, depressive symptoms were concurrently associated with both DIS and DMS, but only predicted subsequent DIS, not DMS.

conclusionsThese findings underscore the bidirectional yet distinct relationships between specific insomnia symptoms and depression in older adults. DIS shows consistent bidirectional associations with depressive symptoms, while DMS is only concurrently associated. Understanding the specific interplay between these conditions may enable the development of more targeted and effective prevention and treatment strategies. CLINICAL TRIAL NUMBER: Not applicable.

Indexed as

DepressionSleep Initiation and Maintenance DisordersAgedAged, 80 and overFemaleHumansIndependent LivingLongitudinal StudiesMalePrevalenceProspective StudiesSelf ReportSurveys and QuestionnairesUnited StatesDepressionDifficulty initiating sleepDifficulty maintaining sleepInsomnia symptomsOlder adults

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.