Evidence map›Paper›PMID 42224814›Full record

ArticleSocial science & medicine (1982)2026

Financial, housing, food, and healthcare insecurities and their independent and joint associations with depressive symptoms and stress in a U.S. cohort of adults with and without HIV.

Hilary J Bethancourt, Bulent Turan, Audrey L Richards, Andrea Norcini-Pala, Sigal Maya, Kartika Palar, Henry J Whittle, Mirjam-Colette Kempf, Katherine C Wu, Jorge R Kizer and 12 more

Abstract read
In one paragraph

Article in Social science & medicine (1982), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Hilary J BethancourtDepartment of Medicine, University of California San Francisco, San Francisco, CA, USA. Electronic address: Hilary.Bethancourt@ucsf.edu.
Bulent TuranDepartment of Psychology, Koc University, Istanbul, Turkey.
Audrey L RichardsDepartment of Health Promotion, Education, and Behavior, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA.
Andrea Norcini-PalaSUNY Downstate Health Sciences, Brooklyn, NY, USA.
Sigal MayaDepartment of Medicine, University of California San Francisco, San Francisco, CA, USA.
Kartika PalarDepartment of Medicine, University of California San Francisco, San Francisco, CA, USA.
Henry J WhittleDepartment of Anthropology and Sociology, SOAS University of London, London, UK.
Mirjam-Colette KempfSchools of Nursing, Medicine, and Public Health, University of Alabama at Birmingham, Birmingham, AL, USA.
Katherine C WuDepartment of Medicine, Division of Cardiology, Johns Hopkins University, Baltimore, MD, USA.
Jorge R KizerDepartment of Medicine, Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, USA; Cardiology Section, San Francisco Veterans Affairs Health System, San Francisco, CA, USA.
Phyllis C TienDepartment of Medicine, University of California San Francisco, San Francisco, CA, USA; Infectious Diseases Section, San Francisco Veterans Affairs Health System, San Francisco, CA, USA.
David B HannaDepartment of Epidemiology & Population Health, Albert Einstein College of Medicine, Bronx, NY, USA.
Allison A AppletonDepartment of Epidemiology and Biostatistics, University at Albany College of Integrated Health Sciences, Albany, NY, USA.
Daniel MerensteinDepartment of Family Medicine, Georgetown University, Washington, DC, USA.
Gypsyamber D'SouzaDepartment of Epidemiology, Johns Hopkins University, Baltimore, MD, USA.
Igho OfotokunSchool of Medicine, Emory University, Atlanta, GA, USA.
Deborah Konkle-ParkerSchools of Nursing, Medicine, and Population Health, University of Mississippi Medical Center, Jackson, MS, USA.
Erin D MichosDepartment of Medicine, Division of Cardiology, Johns Hopkins University, Baltimore, MD, USA; Department of Epidemiology, Johns Hopkins University, Baltimore, MD, USA.
Sarah KrierInfectious Diseases & Microbiology, University of Pittsburgh, Pittsburgh, PA, USA.
Valentina StosorSchool of Medicine, Northwestern University, Evanston, IL, USA.
Sheri D WeiserDepartment of Medicine, University of California San Francisco, San Francisco, CA, USA.
Edward A FrongilloDepartment of Health Promotion, Education, and Behavior, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA.

Funding

Virology CoreP30AI027767 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Renee A. Heffron · 1988 to 2026
$84.1M
Engaging University of California Stakeholders for Biorespository ResearchUL1TR000004 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GRANDIS, JENNIFER RUBIN · 2012 to 2015
$78.0M
Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
Virology and Molecular Biomarkers CoreP30AI050409 · NIAID · EMORY UNIVERSITY · PI Robert H Lyles · 2002 to 2026
$74.0M
QAQC Johns Hopkins Institute for Clinical and Translational ResearchUL1TR003098 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2019 to 2023
$57.7M
Maternal Morbidity and Mortality: Risk Factors, Early Detection and Personalized InterventionUL1TR001409 · NCATS · GEORGETOWN UNIVERSITY · PI GONDRE-LEWIS, MARJORIE C, MELLMAN, THOMAS A · 2015 to 2024
$37.8M
Clinical Research Sites for the MACS/WIHS Combined Cohort Study (MACS/WIHS-CCS) - Baltimore/Wash DC Center - Admin Supplement: Vision and dual sensory loss in HIV-infected older adultsU01HL146201 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI TODD T BROWN, Joseph B. Margolick · 2019 to 2026
$33.7M
Sex differences in the role of multi-omics in HIV-associated carotid artery atherosclerosisU01HL146204 · NHLBI · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI David B. Hanna, Anjali Sharma · 2019 to 2026
$33.2M
University of Pittsburgh MWCCS Clinical Research SiteU01HL146208 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Bernard Jonas C Macatangay, CHARLES R RINALDO · 2019 to 2026
$32.2M
Study of Hearing and Balance in Middle Aged and Aging Men and Women in the MACS-WIHS Combined Cohort StudyU01HL146333 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Roger Detels, Matthew James Mimiaga · 2019 to 2026
$32.2M
Northwestern CORE Clinical Research Site: Trans-omics for HIV/AIDS ResearchU01HL146240 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Frank J Palella, Valentina Stosor · 2019 to 2026
$31.5M
MACS/WIHS Combined Cohort Study Clinical Research SiteU01HL146241 · NHLBI · EMORY UNIVERSITY · PI Cecile Delille Lahiri, Anandi Nayan Sheth · 2019 to 2026
$24.2M
NCATS NIH HHS KL2 TR001432NCATS NIH HHS TL1 TR001431NCATS NIH HHS UL1 TR000004NCATS NIH HHS UL1 TR001409NCATS NIH HHS UL1 TR003098NHLBI NIH HHS R01 HL155226NHLBI NIH HHS U01 HL146192NHLBI NIH HHS U01 HL146201NHLBI NIH HHS U01 HL146202NHLBI NIH HHS U01 HL146203NHLBI NIH HHS U01 HL146204NHLBI NIH HHS U01 HL146208NHLBI NIH HHS U01 HL146240NHLBI NIH HHS U01 HL146241NHLBI NIH HHS U01 HL146245NHLBI NIH HHS U01 HL146333NIAID NIH HHS P30 AI027767NIAID NIH HHS P30 AI050409NIAID NIH HHS P30 AI050410NICHD NIH HHS P2C HD042828NIMH NIH HHS K01 MH125724NIMH NIH HHS R01 MH131177
6 · The paper itself

Abstract

Financial, housing, food, and healthcare insecurities are prevalent forms of material-need insecurity (MNI) in the U.S. that often co-occur, with significant consequences for health. We investigated how these MNIs overlap and relate jointly and independently to mental health among people with and without HIV enrolled in the MACS/WIHS Combined Cohort Study (MWCCS). Confirmatory bifactor analyses were used to examine how much unique variability remained in subfactors for financial, housing, food, and healthcare insecurities after accounting for common, underlying material hardship, described herein as overall MNI severity (n = 2433). Structural equation models tested how overall and specific MNI severity relate independently to depressive symptoms, as measured by the Center for Epidemiologic Studies Depression scale, and perceived stress, as measured by the Perceived Stress Scale, adjusting for income and other socioeconomic covariates. Most of the variance in financial (76.2%), housing (88.7%), food (55.7%), and healthcare insecurity (64.4%) was explained by overall MNI severity, which was strongly related to depressive symptoms (standardized β: 0.508, SE: 0.028, p < 0.001) and perceived stress (standardized β: 0.538, SE: 0.026, p < 0.001). Independently of overall MNI severity and each other, the specific subfactors had additive associations with depressive symptoms and stress. In summary, financial, housing, food, and healthcare insecurities were strongly interrelated, and both their overlapping and distinct characteristics related independently and additively to depressive symptoms and perceived stress. These findings highlight the value of moving beyond studying MNIs in isolation to examining the health consequences of co-occurring MNIs and developing interventions and policies that improve multiple forms of MNIs simultaneously.

Indexed as

DepressionFood InsecurityFood SupplyHIV InfectionsHousingSubjective StressAdultCohort StudiesFemaleHumansMaleMiddle AgedSocioeconomic FactorsUnited StatesBifactor modelsFinancial insecurityFood insecurityHealthcare insecurityHousing insecurityIntersecting needsMental health

Identifiers

PMID42224814
PMCPMC13552194

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.