ArticleJournal of cardiothoracic surgery2026
Conventional preoperative parameters associated with new-onset atrial fibrillation after TAVR: a comparative single-center study.
Article in Journal of cardiothoracic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectivesThis study compared conventional preoperative parameters between transcatheter aortic valve replacement (TAVR) patients with and without post-procedural new-onset atrial fibrillation (NOAF) to identify simple risk markers.
methodsA total of 211 patients undergoing TAVR were enrolled. Post-procedural NOAF occurred in 19 patients (9.0%). Preoperative clinical baseline data, electrocardiographic parameters, conventional echocardiographic indices, laboratory findings, and perioperative variables were compared between the NOAF and No-NOAF groups.
resultsCompared with the No-NOAF group, patients with post-TAVR NOAF were significantly older (P = 0.002) and had a higher heart rate (P = 0.002). Echocardiographically, the NOAF group exhibited larger cardiac dimensions, including right ventricular diameter (P < 0.001), pulmonary artery diameter (P = 0.003), right atrial transverse diameter (P < 0.001), left atrial diameter (P = 0.042), and left ventricular diameter (P = 0.018). Moreover, the NOAF group had lower left ventricular ejection fraction (P = 0.005) and fractional shortening (P = 0.006). Laboratory findings showed significantly higher levels of indirect bilirubin, serum creatinine, uric acid, monocyte percentage, and N-terminal pro-brain natriuretic peptide (NT-proBNP) (P < 0.001), as well as lower glomerular filtration rate and total cholesterol (P = 0.009) in the NOAF group. No significant differences were observed in procedure length, valve type, or intraoperative complications (P > 0.05).
conclusionsOlder age, higher heart rate, enlarged cardiac chambers (including right heart and left atrium), reduced left ventricular systolic function, elevated NT-proBNP, renal dysfunction, higher uric acid, lower total cholesterol, and increased monocyte percentage are associated with post-TAVR NOAF. These easily accessible conventional markers may facilitate early identification of high-risk patients in routine clinical practice, offering a practical alternative to advanced imaging techniques.
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