ArticleDigital health
Sex-specific effects of digital home-based neuromodulation combined with mindfulness-based meditation on knee osteoarthritis symptoms.
Article in Digital health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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8 authors.
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Abstract
Objectives: We evaluated the effects of digital home-based transcranial direct current stimulation (tDCS) paired with audio-delivered mindfulness-based meditation (MBM) on knee-specific clinical pain and symptoms in patients with symptomatic knee osteoarthritis, assessed using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). As sex is a major source of variability in responses to tDCS and MBM, we examined treatment effects by sex. Methods: Participants ( Results: The sample was predominantly female (69.0%). Among females, only the active tDCS + active MBM group showed significantly greater reductions in WOMAC total scores-particularly in physical function-compared to the sham tDCS + sham MBM group immediately post-intervention ( Conclusions: Although digital home-based tDCS paired with MBM may improve knee-specific symptoms, this effect was observed only among females and was short-term. Furthermore, findings should be interpreted cautiously given the sex imbalance.
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