Evidence map›Paper›PMID 42227014›Full record

ArticleHorticulture research2026

Chloroplast-to-apoplast relocalization of MOC1 strengthens plant vascular immunity.

Xinya Du, Yijie Liu, Sai Yuan, Pengyue Li, Yingshuang Liu, Yang Lin, Meng Yuan, Jiatao Xie, Jiangsen Cheng, Yanping Fu and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Horticulture research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Xinya DuState Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, Hubei 430070, China.ORCID https://orcid.org/0000-0002-8254-0785
Yijie LiuState Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, Hubei 430070, China.
Sai YuanState Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, Hubei 430070, China.
Pengyue LiState Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, Hubei 430070, China.ORCID https://orcid.org/0000-0003-4684-2265
Yingshuang LiuHubei Hongshan Laboratory, Wuhan, Hubei 430070, China.
Yang LinThe Provincial Key Lab of Plant Pathology of Hubei Province, College of Plant Science and Technology, Huazhong Agricultural University, Wuhan, Hubei 430070, China.ORCID https://orcid.org/0000-0003-3942-7063
Meng YuanHubei Hongshan Laboratory, Wuhan, Hubei 430070, China.ORCID https://orcid.org/0000-0003-1381-9202
Jiatao XieState Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, Hubei 430070, China.ORCID https://orcid.org/0000-0003-1961-0338
Jiangsen ChengState Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, Hubei 430070, China.ORCID https://orcid.org/0000-0003-0040-2360
Yanping FuThe Provincial Key Lab of Plant Pathology of Hubei Province, College of Plant Science and Technology, Huazhong Agricultural University, Wuhan, Hubei 430070, China.ORCID https://orcid.org/0000-0003-4309-7431
Daohong JiangState Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, Hubei 430070, China.ORCID https://orcid.org/0000-0002-3862-7461
Xiao YuState Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, Hubei 430070, China.ORCID https://orcid.org/0000-0003-2973-3075
Bo LiState Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, Hubei 430070, China.ORCID https://orcid.org/0000-0002-7337-0112

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pathogenic bacteria deploy biofilm as a key virulence factor to cause plant vascular diseases, which are devastating to global agricultural practices. Extracellular DNA (eDNA) constitutes the backbone of bacterial biofilm and is key to biofilm stability, thereby representing as an attractive therapeutic target. Here, we engineered the plant chloroplast-localized Holliday junction (HJ) resolvase MOC1 by replacing its native chloroplast transit peptide with a secretory signal, successfully relocating it to the apoplast. Transgenic tomato and rice expressing secreted MOC1 exhibited robust resistance to bacterial wilt and bacterial blight, respectively, without growth or yield penalties. Additionally, we implemented bacterial pathogen-inducible promoters to achieve precisely spatial and temporal control over the resistance trait. Secreted MOC1 degrades eDNA

Identifiers

PMID42227014
PMCPMC13222483

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.