Evidence map›Paper›PMID 42228089›Full record

ReviewDermatologie (Heidelberg, Germany)2026

[Chronic prurigo: overview of pathophysiology, diagnosis, and treatment].

Felix Witte, Claudia Zeidler, Sonja Ständer

Abstract readEnglish AbstractReview
PubMed Publisher
In one paragraph

Review in Dermatologie (Heidelberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Felix WitteSektion Pruritusmedizin, Kompetenzzentrum Chronischer Pruritus (KCP) und Klinik für Hautkrankheiten, Universitätsklinikum Münster, Von-Esmarch-Str. 58, 48149, Münster, Deutschland. felix.witte@ukmuenster.de.
Claudia ZeidlerSektion Pruritusmedizin, Kompetenzzentrum Chronischer Pruritus (KCP) und Klinik für Hautkrankheiten, Universitätsklinikum Münster, Von-Esmarch-Str. 58, 48149, Münster, Deutschland.
Sonja StänderSektion Pruritusmedizin, Kompetenzzentrum Chronischer Pruritus (KCP) und Klinik für Hautkrankheiten, Universitätsklinikum Münster, Von-Esmarch-Str. 58, 48149, Münster, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic prurigo (CPG) remains a challenging disease. Besides diagnosis, which mostly relies on the S2k-guideline diagnosis and treatment of chronic pruritus, two systemic agents have been approved for the treatment of CPG in recent years.

objectivesThis review aims to provide an overview of the pathophysiology and current diagnostic and therapeutic recommendations for CPG. MATERIALS AND

methodsFor this review, a literature and clinical trial search was conducted via PubMed and Clinical Trials using the terms 'chronic prurigo', 'prurigo nodularis', 'pathophysiology', 'diagnosis', 'treatment' and 'therapy'. RESULTS AND

conclusionThe pathophysiology of CPG is becoming increasingly well understood. Building on this, a second targeted therapy for patients with moderate to severe CPG has recently been approved. Numerous other substances are currently undergoing clinical trials, offering the prospect of further improvements in the care of patients affected by CPG.

Indexed as

PrurigoAntibodies, Monoclonal, HumanizedChronic DiseaseHumansPruritusAntibodies, Monoclonal, HumanizeddupilumabnemolizumabDupilumabNemolizumabPrurigo nodularisPruritusTargeted therapy

Identifiers

PMID42228089

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.