Evidence map›Paper›PMID 42230489›Full record

ArticleBulletin of experimental biology and medicine2026

Histomorphometric Evaluation of the Tissue Response to Xenogeneic Extracellular Peritoneal Matrix and Synthetic UltraPro Mesh under Conditions of Pseudomonas aeruginosa Infection.

N T Abatov, R M Badyrov, N K Urazbayev, E K Kamyshanskiy, A V Lavrinenko, L L Akhmaltdinova, D K Esniyazov

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Article in Bulletin of experimental biology and medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

7 authors.

N T AbatovKaraganda Medical University, Karaganda, Kazakhstan.
R M BadyrovKaraganda Medical University, Karaganda, Kazakhstan.
N K UrazbayevKaraganda Medical University, Karaganda, Kazakhstan. nurik_7663@mail.ru.
E K KamyshanskiyKaraganda Medical University, Karaganda, Kazakhstan.
A V LavrinenkoKaraganda Medical University, Karaganda, Kazakhstan.
L L AkhmaltdinovaKaraganda Medical University, Karaganda, Kazakhstan.
D K EsniyazovKaraganda Medical University, Karaganda, Kazakhstan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We performed a comparative histomorphometric assessment of the tissue responses to two types of implants, xenogeneic extracellular peritoneal matrix (ECM) and synthetic UltraPro mesh, in laboratory rats with modeled Pseudomonas aeruginosa infection. Histological evaluation was carried out on days 10 and 20 after implantation of the tested materials under the anterior abdominal wall. ECM induced a pronounced inflammatory response accompanied by tissue necrosis at early post-implantation terms and followed by progressive tissue remodeling. In contrast, the UltraPro mesh induced a milder acute inflammatory reaction with a tendency toward chronic inflammation and fibrous capsule formation. This findings support the importance of evaluating the infectious burden during implant selection in clinical practice.

Indexed as

Extracellular MatrixPeritoneumPseudomonas InfectionsSurgical MeshAbdominal WallAnimalsMalePseudomonas aeruginosaRatsRats, WistarhistomorphometryimplantPseudomonas aeruginosaUltraProxenogeneic extracellular peritoneal matrix

Identifiers

PMID42230489

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.