Evidence map›Paper›PMID 42230865›Full record

ArticleScientific reports2026

Saliva-based monitoring of chronic kidney disease: comparative evaluation of three collection methods for creatinine, urea, calcium, and PTH.

Mohammad Abu Raihan Uddin, Tuan Salwani Tuan Ismail, Wan Nor Fazila Hafizan Wan Nik, Wan Nor Arifin, Salbiah Isa, Noor Huda Ismail, Muhammad Imran Kamarudin

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mohammad Abu Raihan UddinDepartment of Chemical Pathology, School of Medical Sciences, Universiti Sains Malaysia, Kota Bharu, Kelantan, 16150, Malaysia.
Tuan Salwani Tuan IsmailDepartment of Chemical Pathology, School of Medical Sciences, Universiti Sains Malaysia, Kota Bharu, Kelantan, 16150, Malaysia. tusti@usm.my.
Wan Nor Fazila Hafizan Wan NikDepartment of Chemical Pathology, School of Medical Sciences, Universiti Sains Malaysia, Kota Bharu, Kelantan, 16150, Malaysia. wanfazila@usm.my.
Wan Nor ArifinBiostatistics and Research Methodology Unit, School of Medical Sciences, Universiti Sains Malaysia, Kota Bharu 16150, Kelantan, Malaysia.
Salbiah IsaLife Style Science Cluster, Advanced Medical and Dental Institute, Universiti Sains Malaysia, Kepala Batas 13200, Pulau Pinang, Sains@ Bertam, Malaysia.
Noor Huda IsmailSchool of Dental Sciences, Universiti Sains Malaysia, Health Campus, Kota Bharu, Kelantan, 16150, Malaysia.
Muhammad Imran KamarudinDepartment of Internal Medicine, School of Medical Sciences, Universiti Sains Malaysia, Kota Bharu, Kelantan, 16150, Malaysia.

Funding

Universiti Sains Malaysia 2025/163/BG480 (Project No. R501-LR-RND002-0000000096-0000)
6 · The paper itself

Abstract

Chronic kidney disease (CKD) requires regular biochemical monitoring of renal function and mineral metabolism; however, the invasiveness of serum-based testing limits frequent assessment, prompting interest in saliva as a non-invasive alternative despite ongoing challenges related to collection methods and biomarker specific limitations. In this cross-sectional study, paired saliva and serum samples were collected from 47 healthy adults and 47 CKD patients. Saliva was obtained via passive drool, Salivette

Indexed as

CalciumCreatinineParathyroid HormoneRenal Insufficiency, ChronicSalivaSpecimen HandlingUreaAdultAgedBiomarkersCross-Sectional StudiesFemaleHumansMaleMiddle AgedBiomarkersCalciumCreatinineParathyroid HormoneUreaCalciumChronic kidney diseaseCotton rollCreatinineNoninvasive diagnosticsParathyroid hormoneRenal function monitoringSaliva collection methodsSalivary biomarkersUrea

Identifiers

PMID42230865
PMCPMC13469623

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.