ArticleAsia-Pacific journal of sports medicine, arthroscopy, rehabilitation and technology2026
Correlation between functional impairment and quantitative MRI assessment of ankle cartilage in chronic ankle instability.
Article in Asia-Pacific journal of sports medicine, arthroscopy, rehabilitation and technology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Chronic ankle instability (CAI) is characterized by persistent ankle pain, instability, and recurrent sprains. Previous studies have investigated functional impairments and cartilage degeneration separately, but the relationship between them in CAI remains unclear and unexplored. Objective: This study aimed to compare the outcomes of functional impairments and cartilage composition between individuals with CAI and healthy controls to develop targeted interventions to improve joint health and prevent cartilage degeneration in patients with CAI. Methods: This case-control study enrolled 20 individuals with CAI and 25 healthy controls. Dynamic balance measured using the Y-Balance Test (YBT) and static postural control was quantified by analyzing the trajectory of the center of pressure (CoP). T2 mapping of the talocrural joint was conducted using a 3-T magnetic resonance imaging scanner to assess ankle cartilage composition. Clinical questionnaire such as the Cumberland Ankle Instability Tool (CAIT) was used to evaluate the self-reported functional instability. Results: The T2 values were significantly higher in medial center (MC), medial posterior (MP), and lateral posterior (LP) ( Conclusions: This study provides evidence of functional impairments and cartilage degeneration in individuals with CAI. The observed biomechanical compensations and increased cartilage T2 values may contribute to the development of CAI and potentially increase the risk of long-term joint degeneration. These valuable insights into the pathophysiology of CAI may aid in developing targeted interventions to mitigate long-term joint degeneration.
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