ArticleFrontiers in medicine2026
Current status and influencing factors of laryngopharyngeal reflux disease in outpatients with laryngeal diseases: key considerations for clinical practice.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Laryngopharyngeal reflux disease (LPRD) is a common comorbidity in outpatients with laryngeal diseases, which seriously affects patients' quality of life and treatment outcomes. This study aimed to explore the current status of LPRD comorbidity in outpatients with laryngeal diseases, identify its independent risk factors, and construct a practical prediction model to provide evidence for clinical prevention and early diagnosis. Methods: Outpatients with laryngeal diseases treated in our hospital from August 2024 to August 2025 were included. Demographic characteristics, living habits, comorbidities, and examination indicators were collected and compared. Results: A total of 1,650 outpatients with laryngeal diseases were included. Multivariate Logistic regression analysis confirmed that age ≥65 years, BMI ≥ 25 kg/m Conclusion: LPRD is prevalent among outpatients with laryngeal diseases and is influenced by multiple risk factors. The prediction model developed based on seven independent risk factors demonstrates good diagnostic performance, offering a practical and reliable tool for early identification of high-risk patients.
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