Evidence map›Paper›PMID 42233248›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2026

Validity of the two different scoring methods of the Clinical Dementia Rating scale in staging and detection of cognitive impairment in the Peruvian population.

Junior Senador, Rosa Montesinos, Belén Custodio, Jose Huilca, Katherine Agüero, Graciet Verastegui, Pamela Bartolo, Milagros Nuñez-Huanca, María Fe Albujar Pereira, Nilton Custodio

Abstract readValidation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Junior SenadorUnidad de Investigación de Deterioro Cognitivo y Prevención de Demencia, Instituto Peruano de Neurociencias, Lima, Peru.ORCID https://orcid.org/0009-0006-4718-5470
Rosa MontesinosUnidad de Investigación de Deterioro Cognitivo y Prevención de Demencia, Instituto Peruano de Neurociencias, Lima, Peru.ORCID https://orcid.org/0000-0002-9342-8756
Belén CustodioUnidad de Investigación de Deterioro Cognitivo y Prevención de Demencia, Instituto Peruano de Neurociencias, Lima, Peru.ORCID https://orcid.org/0009-0007-1445-7211
Jose HuilcaUnidad de Investigación de Deterioro Cognitivo y Prevención de Demencia, Instituto Peruano de Neurociencias, Lima, Peru.ORCID https://orcid.org/0000-0001-5561-4702
Katherine AgüeroUnidad de Investigación de Deterioro Cognitivo y Prevención de Demencia, Instituto Peruano de Neurociencias, Lima, Peru.ORCID https://orcid.org/0000-0002-1137-1363
Graciet VerasteguiUnidad de Investigación de Deterioro Cognitivo y Prevención de Demencia, Instituto Peruano de Neurociencias, Lima, Peru.ORCID https://orcid.org/0009-0000-5928-2215
Pamela BartoloUnidad de Investigación de Deterioro Cognitivo y Prevención de Demencia, Instituto Peruano de Neurociencias, Lima, Peru.ORCID https://orcid.org/0009-0002-5959-9241
Milagros Nuñez-HuancaUnidad de Investigación de Deterioro Cognitivo y Prevención de Demencia, Instituto Peruano de Neurociencias, Lima, Peru.ORCID https://orcid.org/0009-0002-0373-9479
María Fe Albujar PereiraUnidad de Investigación de Deterioro Cognitivo y Prevención de Demencia, Instituto Peruano de Neurociencias, Lima, Peru.ORCID https://orcid.org/0000-0002-8102-2003
Nilton CustodioUnidad de Investigación de Deterioro Cognitivo y Prevención de Demencia, Instituto Peruano de Neurociencias, Lima, Peru.ORCID https://orcid.org/0000-0002-8025-3272

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIn Peru, the Global Deterioration Scale is the only available tool for assessing dementia severity. The Spanish translation and cultural adaptation of the Clinical Dementia Rating (CDR) is used locally but requires formal psychometric validation in the Peruvian sociocultural context.

methodsA total of 1,600 older adults: 902 controls, 271 mild cognitive impairment (MCI), and 427 Alzheimer's disease patients (AD) were assessed to validate two CDR scoring methods: CDR Global Score (CDR-GS) and CDR Sum of Boxes Score (CDR-SB). Discriminative validity, inter-item reliability, and concurrent validity were evaluated using MMSE, RUDAS, PFAQ, and Uniform Data Set (UDS) v3 Neuropsychological Battery.

resultsCDR demonstrated high reliability and validity among normal cognition, mild cognitive impairment, and AD. For AD screening, CDR-SB showed 98.2% sensitivity and 99.6% specificity, while CDR-GS demonstrated 99.8% sensitivity and 100% specificity. DISCUSSION: The Peruvian CDR version exhibited good psychometric properties comparable to those reported in Latin American CDR validation studies.

Indexed as

Alzheimer DiseaseCognitive DysfunctionMental Status and Dementia TestsNeuropsychological TestsAgedAged, 80 and overFemaleHumansMaleMiddle AgedPeruPsychometricsReproducibility of ResultsSensitivity and SpecificitySeverity of Illness IndexAlzheimer's diseaseClinical Dementia Rating Scale Global ScoreClinical Dementia Rating Scale Sum of Boxesdementiamild cognitive impairmentPeruvian

Identifiers

PMID42233248
PMCPMC13239292

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.