ArticleDiabetic medicine : a journal of the British Diabetic Association2026
Treatment burden and health-related quality of life in young adults with type 1 diabetes.
Article in Diabetic medicine : a journal of the British Diabetic Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
aimThis study aims to assess the treatment burden and health-related quality of life (HRQoL) in young adults with type 1 diabetes (T1D).
methodsOnline survey on experienced treatment burden (Treatment Burden Questionnaire, TBQ, 0-150, higher scores indicate higher burden) and HRQoL (Type 1 Diabetes and Life questionnaire for ages 18-25 and 26-45, T1DAL, 0-100, higher scores indicate better HRQoL) among Dutch young adults with T1D (aged 18-30).
resultsIn total, 294 young adults with T1D completed the survey. Mean TBQ score was 59.5 (SD = 24.9). Regular medical care reminding participants of their health problems scored highest. Mean T1DAL scores were 55.9 (SD = 12.9) for ages 18-25, and 62.1 (SD = 13.2) for ages 26-30. Lowest scores were in the subcategory 'Emotional experiences and daily activities' (18-25: median = 41.7, IQR = 24.9; 26-30: median = 47.8, IQR = 22.5). TBQ was strongly negatively correlated with T1DAL (r = -0.69, 95% CI [-0.74, -0.62], p < 0.001). Characteristics associated with higher treatment burden and lower HRQoL included female gender, lower time in range and dissatisfaction with diabetes management approach.
conclusionYoung adults with T1D report considerable treatment burden and moderate HRQoL, suggesting a high impact of diabetes care on their lives. Treatment burden is particularly affected by regular medical care activities, whereas diabetes affects the daily functioning and emotional experiences domains of HRQoL. Further research is needed to understand how young adults make care fit and to improve care for these patients, resulting in minimally disruptive care plans. While cautiously interpreted, this may be especially relevant for women and those with adverse clinical outcomes.
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