ArticleJournal of general internal medicine2026
Engagement and Weight Change in an Online Weight Management Program in Clinical Settings: An Implementation Project.
Article in Journal of general internal medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05553925 (Implementation of an Online Weight Management Program in Clinical and Community Settings), which is not on this map. Not yet cited in PubMed.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Implementation of an Online Weight Management Program in Clinical and Community Settings
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Authors and funding
19 authors.
Funding
Abstract
backgroundThere is an urgent need for scalable strategies for treatment of overweight and obesity that can be implemented in clinical settings.
objectiveTo implement and evaluate an online weight management program in a large, diverse population of patients.
designClinical implementation project in primary care and specialty clinics.
participantsEligible patients were ≥ 20 years old, spoke English or Spanish, and had a body mass index (BMI) of ≥ 30 kg/m
interventionEnrolled patients were encouraged to register for a 12-month digital health program called RestoreHealth, which included an online program/app and coaching. MAIN MEASURES: We examined recruitment and enrollment in the program, as well as engagement, absolute and percent weight change, and predictors of weight change during the first six months. Subgroup analyses were conducted by use of anti-obesity medications. KEY
resultsA total of 5056 patients enrolled between November 2022 and October 2023, and 4511 (89.2%) completed registration for RestoreHealth. At six months, mean absolute and percent weight change among all enrolled patients were -5.7 pounds and -2.5%, respectively (p < 0.0001 for both), and 27.7% of patients lost ≥ 5% of their body weight. There was greater weight loss among patients using anti-obesity medications (mean absolute and percent weight change = -12.5 pounds and -5.5%, respectively). Among registered patients, 91.8% engaged in the program, although engagement decreased over time. Older age, greater weight at enrollment, and longer duration of engagement were associated with greater weight loss.
conclusionsWe rapidly enrolled a large, diverse population of patients in PROPS 2.0. Patients lost weight at six months, with greater weight loss among those using anti-obesity medications. This program has the potential to be scaled and implemented at other institutions in the future. CLINICALTRIALS: GOV REGISTRATION NUMBER: NCT05553925 (initial release date August 18, 2022).
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Registered trials
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