Evidence mapPaperPMID 42236102Full record

ArticleBMJ open2026

Tianjin Health and Chronic Disease Study (THCDS): study design and baseline characteristics of the cohort - cohort profile.

Xuerui Li, Yuyang Miao, Jun Zheng, Yiting Zhang, Yifan Hao, Nan Zhang, Shiyin Dai, Wenjing Lin, Qiang Zhang

Abstract read
In one paragraph

Article in BMJ open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xuerui Li *Department of Geriatrics, Key Laboratory of Post-Neuroinjury Neuro-Repair and Regeneration in the Central Nervous System, Ministry of Education, State Key Laboratory of Experimental Hematology, Tianjin Key Laboratory of Elderly Health, Tianjin Geriatrics Institute, Tianjin Medical University General Hospital, Tianjin, China.ORCID http://orcid.org/0009-0000-3704-3838
Yuyang Miao *Department of Geriatrics, Key Laboratory of Post-Neuroinjury Neuro-Repair and Regeneration in the Central Nervous System, Ministry of Education, State Key Laboratory of Experimental Hematology, Tianjin Key Laboratory of Elderly Health, Tianjin Geriatrics Institute, Tianjin Medical University General Hospital, Tianjin, China.
Jun ZhengDepartment of Geriatrics, Key Laboratory of Post-Neuroinjury Neuro-Repair and Regeneration in the Central Nervous System, Ministry of Education, State Key Laboratory of Experimental Hematology, Tianjin Key Laboratory of Elderly Health, Tianjin Geriatrics Institute, Tianjin Medical University General Hospital, Tianjin, China.
Yiting ZhangDepartment of Geriatrics, Key Laboratory of Post-Neuroinjury Neuro-Repair and Regeneration in the Central Nervous System, Ministry of Education, State Key Laboratory of Experimental Hematology, Tianjin Key Laboratory of Elderly Health, Tianjin Geriatrics Institute, Tianjin Medical University General Hospital, Tianjin, China.
Yifan HaoDepartment of Geriatrics, Key Laboratory of Post-Neuroinjury Neuro-Repair and Regeneration in the Central Nervous System, Ministry of Education, State Key Laboratory of Experimental Hematology, Tianjin Key Laboratory of Elderly Health, Tianjin Geriatrics Institute, Tianjin Medical University General Hospital, Tianjin, China.
Nan ZhangDepartment of Geriatrics, Key Laboratory of Post-Neuroinjury Neuro-Repair and Regeneration in the Central Nervous System, Ministry of Education, State Key Laboratory of Experimental Hematology, Tianjin Key Laboratory of Elderly Health, Tianjin Geriatrics Institute, Tianjin Medical University General Hospital, Tianjin, China.
Shiyin DaiDepartment of Geriatrics, Key Laboratory of Post-Neuroinjury Neuro-Repair and Regeneration in the Central Nervous System, Ministry of Education, State Key Laboratory of Experimental Hematology, Tianjin Key Laboratory of Elderly Health, Tianjin Geriatrics Institute, Tianjin Medical University General Hospital, Tianjin, China.
Wenjing LinDepartment of Geriatrics, Key Laboratory of Post-Neuroinjury Neuro-Repair and Regeneration in the Central Nervous System, Ministry of Education, State Key Laboratory of Experimental Hematology, Tianjin Key Laboratory of Elderly Health, Tianjin Geriatrics Institute, Tianjin Medical University General Hospital, Tianjin, China.
Qiang ZhangDepartment of Geriatrics, Key Laboratory of Post-Neuroinjury Neuro-Repair and Regeneration in the Central Nervous System, Ministry of Education, State Key Laboratory of Experimental Hematology, Tianjin Key Laboratory of Elderly Health, Tianjin Geriatrics Institute, Tianjin Medical University General Hospital, Tianjin, China zhangqiangyulv@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe Tianjin Health and Chronic Disease Study (THCDS) is a longitudinal dynamic cohort study established in 2022, aiming to investigate risk factors and intervention targets of common non-communicable diseases (NCDs) in Tianjin, China.

participantsA total of 14 324 participants (average age: 53.48, 34.8% females) were recruited for the baseline survey from July 2022 to November 2023. All participants underwent routine medical examination, including anthropometric (height, weight and blood pressure), ECG, colour Doppler ultrasound (thyroid, carotid artery, heart, abdominal and reproductive system), chest imaging measurements (X-ray or computerised tomographic scanning), and plasma, urine and faeces sample test and a standardised questionnaire, including demographic information, lifestyle factors (smoking, alcohol consumption, diet, sleep factors, physical activity, cognitive activity and social activity) and self-reported history of common chronic diseases. Participants older than 60 were also invited to perform cognitive function tests using the Montreal Cognitive Assessment scale. Follow-ups were tracked annually through routine medical examinations and standardised questionnaires to detect their health status. FINDINGS TO DATE: Key baseline findings revealed sex disparities in disease prevalence and clinical characteristics, with males showing higher rates of hypertension (46.60% vs 34.23%), type 2 diabetes (17.39% vs 9.54%) and gout (33.47% vs 15.59%), while females had higher prevalence of hyperlipidaemia (15.47% vs 18.26%), insomnia (5.42% vs 10.00%) and cancer (1.75% vs 3.23%) (all p<0.05). Females demonstrated higher cognitive scores but lower scores in naming/abstraction compared with males. Furthermore, based on the baseline data, we also found that the combined elevation of fasting glucose and serum uric acid levels significantly correlates with non-alcoholic fatty liver disease, especially in individuals without self-reported diabetes status. FUTURE PLANS: THCDS is an ongoing prospective cohort with long-term follow-up (at least 15 years). Ongoing follow-ups will be used to investigate longitudinal trajectories of risk factors and chronic diseases and to identify modifiable determinants to inform NCD prevention strategies. TRIAL REGISTRATION NUMBER: ChiCTR2400083075; pre-result.

Indexed as

Noncommunicable DiseasesAdultAgedChinaChronic DiseaseFemaleHumansHypertensionLife StyleLongitudinal StudiesMaleMiddle AgedPrevalenceResearch DesignRisk FactorsSurveys and QuestionnairesChronic DiseaseEPIDEMIOLOGYPhysical ExaminationPUBLIC HEALTHSurveys and Questionnaires

Identifiers

PMID42236102
PMCPMC13239659

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.