ReviewAnnals of neurosciences2026
Mind-Body Interventions as Modulators of Neural Connectivity and Cognition in Individuals at Risk for Alzheimer's Disease: A Systematic Review.
Review in Annals of neurosciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Alzheimer's disease (AD) is the leading cause of dementia worldwide, contributing to nearly 60%-70% of dementia cases. Current pharmacological treatments provide limited symptomatic relief and minimal efficacy in altering disease progression, highlighting the need for complementary interventions. Mind-body practices such as yoga and meditation are increasingly explored for preserving cognitive abilities and reducing neurodegenerative risk. Summary: This systematic review evaluated randomized controlled trials investigating yoga, meditation, and related mind-body interventions on cognitive and neural health in individuals with normal cognition, mild cognitive impairment, or subjective memory decline. Following PRISMA guidelines, studies published up to March 2025 were reviewed. Findings showed improvements in memory, attention, executive functions, mood, and quality of life. Neurobiological benefits included preservation of hippocampal volume, improved functional connectivity, increased brain-derived neurotrophic factor levels, and reduced neuroinflammation markers. However, methodological limitations such as small sample sizes and short intervention durations were common. Key Message: Mind-body interventions show promising cognitive and neurobiological benefits in populations at risk of AD. Yoga and meditation may serve as feasible, cost-effective complementary approaches alongside conventional therapy. Larger long-term clinical trials are needed to establish standardized protocols and sustained therapeutic effectiveness.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.