Evidence map›Paper›PMID 42238357›Full record

ArticleInternational journal of general medicine2026

Factors Associated with Malignant Gastric Ulcers: A 10-year Retrospective Cohort Study.

Anas Zayad, Yousef Yahia, Prem Chandra, Ibrahim Obeidat, Mohamad Safieh, Sadi Alnakhala, Husam A Saffo

Abstract read
In one paragraph

Article in International journal of general medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Anas ZayadInternal Medicine Department, Hamad Medical Corporation, Doha, Qatar.ORCID 0009-0006-7537-0112
Yousef YahiaGastroenterology and Hepatology Department, Hamad Medical Corporation, Doha, Qatar.ORCID 0000-0002-8468-3499
Prem ChandraMedical Research Center, Hamad Medical Corporation, Doha, Qatar.
Ibrahim ObeidatGastroenterology and Hepatology Department, Hamad Medical Corporation, Doha, Qatar.
Mohamad SafiehInternal Medicine Department, Hamad Medical Corporation, Doha, Qatar.ORCID 0009-0006-9621-1436
Sadi AlnakhalaGastroenterology and Hepatology Department, Hamad Medical Corporation, Doha, Qatar.
Husam A SaffoGastroenterology and Hepatology Department, Hamad Medical Corporation, Doha, Qatar.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Gastric ulcers carry a recognized risk of underlying malignancy. Regional evidence remains limited in the Middle East, where historically high Methods: A retrospective cohort of all patients diagnosed with gastric ulcer between 2014 and 2024 at Hamad Medical Corporation was analyzed. Local protocols mandate biopsy and follow-up endoscopy, although real-world adherence varies. Collected variables included demographics, ulcer morphology, Results: Among 473 patients, 39 (8.2%) had malignant ulcers. Ulcer size was the strongest predictor of malignancy; medium and large ulcers demonstrated markedly increased odds in univariate and multivariable analyses. Age, sex, smoking, alcohol use, Conclusion: Malignant gastric ulcers accounted for a meaningful minority of ulcer presentations. Ulcer size was the dominant predictor of malignancy, while demographic, lifestyle, and microbial factors added limited discriminatory value. These findings support emphasizing ulcer size in risk stratification and ensuring universal biopsy of all gastric ulcers, with timely follow-up for medium and large lesions.

Indexed as

endoscopygastric cancergastric ulcerHelicobacter pylorimalignancy riskmiddle east epidemiologypredictive factorsreal-world studyretrospective cohortulcer size

Identifiers

PMID42238357
PMCPMC13228842

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.