ReviewArchivos peruanos de cardiologia y cirugia cardiovascular
Cardiac magnetic resonance parameters associated with myocarditis in patients treated with immunotherapy: a scoping review.
Review in Archivos peruanos de cardiologia y cirugia cardiovascular. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This scoping review, conducted in accordance with the PRISMA-ScR methodology, maps the available scientific evidence on cardiac magnetic resonance (CMR) abnormalities associated with immune checkpoint inhibitor-induced myocarditis (ICI-M). Twenty studies published between 2019 and 2025 were analysed, highlighting alterations in left ventricular function (left ventricular ejection fraction [LVEF]), myocardial oedema detected by T2-weighted sequences, and fibrosis identified as late gadolinium enhancement (LGE). Key diagnostic criteria included elevated extracellular volume (ECV), impaired global longitudinal strain (GLS), and abnormal T1 and T2 relaxation times. Of the included studies, most were retrospective, followed by case reports and prospective studies. The therapies most frequently associated with ICI-M involved combinations of anti-PD1 and anti-CTLA4 agents. Cardiac magnetic resonance (CMR) has proven to be a highly sensitive, non-invasive tool for detecting myocardial involvement, even before the elevation of biomarkers such as troponins. The importance of using advanced tools like CMR to assess cardiovascular complications associated with myocarditis is highlighted. Parameters such as LVEF, GLS, LGE, and ECV provide valuable information on ventricular function and structural alterations related to myocarditis. These findings allow us to identify knowledge gaps and guide future research on the use of CMR in myocarditis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.