Evidence mapPaperPMID 42238641Full record

ReviewReviews in cardiovascular medicine2026

Cardiac Responses to Alcohol: A Review of Mechanisms and Clinical Implications.

Kristine E Johnston, Aishwarya Kamble, Joanna Lee, Kayla Garley, Vincent M Figueredo

Abstract readReview
In one paragraph

Review in Reviews in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kristine E JohnstonDepartment of Medicine, St Mary Medical Center, Langhorne, PA 19047, USA.ORCID https://orcid.org/0009-0007-4744-8012
Aishwarya KambleDepartment of Medicine, St Mary Medical Center, Langhorne, PA 19047, USA.ORCID https://orcid.org/0009-0002-3541-1697
Joanna LeeDepartment of Medicine, St Mary Medical Center, Langhorne, PA 19047, USA.ORCID https://orcid.org/0000-0003-1519-1631
Kayla GarleyDepartment of Medicine, St Mary Medical Center, Langhorne, PA 19047, USA.ORCID https://orcid.org/0009-0001-3870-9360
Vincent M FigueredoDivision of Cardiology, St Mary Medical Center, Langhorne, PA 19047, USA.ORCID https://orcid.org/0000-0002-3448-2314

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alcohol has been appreciated by civilizations for thousands of years. Nonetheless, alcohol has recently been linked to serious cardiovascular diseases. Therefore, this review summarizes the effects of alcohol on the heart based on the most current literature available. This review covers the effects of alcohol on blood pressure (BP), heart rate (HR), autonomic dysfunction, coronary artery disease (CAD), cardiomyopathy, and cardiac arrhythmias. Evidence supports the harmful effects of both acute (binge) and chronic heavy alcohol consumption on BP, HR, autonomic dysfunction, and the risk of CAD, cardiomyopathy, and various arrhythmias. Some studies suggest that mild to moderate drinking may reduce the risk of CAD and arrhythmias, consistent with a potential J-shaped relationship. However, other evidence contradicts this, thereby indicating that alcohol use may increase the risk of developing hypertension, CAD, and atrial fibrillation. At the time of this review, evidence supports the harmful effects of acute and chronic heavy alcohol consumption on the heart. Findings are mixed for mild to moderate drinking and may be influenced by confounding factors, underscoring the need for further research. Given the inconclusive benefits, the authors recommend that no level of alcohol consumption be promoted as beneficial for cardiac health.

Indexed as

alcoholarrhythmiablood pressurecardiaccardiomyopathycoronary artery diseaseheart

Identifiers

PMID42238641
PMCPMC13227384

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.