ArticlebioRxiv : the preprint server for biology2026
FTO separation-of-function mutations alter m
Kasun Dilshan Abeyrathne Eluwawalage, Brittany Shimanski, Marcin Warminski, Suma Katta, Rebecca Payne, Yanbao Yu, Joanna Kowalska, Jacek Jemielity, Jeffrey S Mugridge
Abstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from itWhat it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
9 authors.
Kasun Dilshan Abeyrathne EluwawalageDepartment of Chemistry & Biochemistry, University of Delaware, Newark, DE 19716, United States.
Brittany ShimanskiDepartment of Chemistry & Biochemistry, University of Delaware, Newark, DE 19716, United States.
Marcin WarminskiDivision of Biophysics, Institute of Experimental Physics, Faculty of Physics, University of Warsaw, 02-093 Warsaw, Poland.
Suma KattaDepartment of Chemistry & Biochemistry, University of Delaware, Newark, DE 19716, United States.
Rebecca PayneDepartment of Chemistry & Biochemistry, University of Delaware, Newark, DE 19716, United States.
Yanbao YuDepartment of Chemistry & Biochemistry, University of Delaware, Newark, DE 19716, United States.ORCID 0000-0003-2994-1974 Joanna KowalskaDivision of Biophysics, Institute of Experimental Physics, Faculty of Physics, University of Warsaw, 02-093 Warsaw, Poland.ORCID 0000-0002-9174-7999 Jacek JemielityCentre of New Technologies, University of Warsaw, 02-097 Warsaw, Poland.
Jeffrey S MugridgeDepartment of Chemistry & Biochemistry, University of Delaware, Newark, DE 19716, United States.ORCID 0000-0002-1553-3008 Funding
This renovation project will create over 1455 sq. ft. of state- of-the-art reseaP20GM104316 · NIGMS · UNIVERSITY OF DELAWARE · PI FOX, JOSEPH M · 2014 to 2024
$26.8MSelectivity and regulation of mRNA demethylation by iron-dependent dioxygenasesR35GM143000 · NIGMS · UNIVERSITY OF DELAWARE · PI MUGRIDGE, JEFFREY SCOTT · 2021 to 2025
$2.1MNIGMS NIH HHS P20 GM104316NIGMS NIH HHS R35 GM143000
6 · The paper itselfAbstract
The RNA demethylase FTO erases N6-methyladenosine (m
Indexed as
enzyme engineeringepitranscriptomicsFTOm6Am6AmRNA demethylation
Identifiers
PMID42239405
PMCPMC13228208
What Socratic holds
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