Evidence map›Paper›PMID 42239636›Full record

ArticleOsteoarthritis imaging2025

Exploratory analysis of infrapatellar fat pad MRI-based radiomics for detection of knee structure abnormalities in collegiate basketball players and swimmers.

Jack Consolini, Kevin M Koch, Alissa J Burge, Erwin Xia, Sharmila Majumdar, Garry E Gold, Hollis G Potter, Matthew F Koff

Abstract read
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Article in Osteoarthritis imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jack ConsoliniDepartment of Radiology and Imaging, Hospital for Special Surgery, New York, NY, USA.
Kevin M KochDepartment of Radiology and Imaging, Hospital for Special Surgery, New York, NY, USA.
Alissa J BurgeDepartment of Radiology and Imaging, Hospital for Special Surgery, New York, NY, USA.
Erwin XiaDepartment of Radiology and Imaging, Hospital for Special Surgery, New York, NY, USA.
Sharmila MajumdarDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, USA.
Garry E GoldDepartment of Radiology, Stanford University, Stanford CA, USA.
Hollis G PotterDepartment of Radiology and Imaging, Hospital for Special Surgery, New York, NY, USA.
Matthew F KoffDepartment of Radiology and Imaging, Hospital for Special Surgery, New York, NY, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Magnetic resonance imaging (MRI) based radiomic evaluation of the infrapatellar fat pad (IPFP) has been shown to predict knee osteoarthritis. As IPFP abnormalities can arise from sport-related injuries, this study evaluated whether qualitatively identified knee structure abnormalities in young athletes can be detected by IPFP MRI-based radiomics. Design: Bilateral knee MRIs using Dixon fat-water decomposition techniques were obtained from 46 NCAA Division 1 collegiate 46 basketball players (26 male, 20 female) and 21 swimmers (10 male, 11 female). Board-certified musculoskeletal radiologists evaluated anatomic features and patellar height using the modified Noyes score and Caton-Deschamps index. IPFP volumes were segmented, and fat fraction was computed. Radiomic features were calculated within 2D overlapping patches extracted from the IPFP in the fat and water images separately. Cross-validated logistic regression models were developed using IPFP radiomic features as predictors of an athlete's sport and the occurrence of cartilage lesions, tendinopathy, or bone abnormalities as observed on MRI. Mann-Whitney U tests evaluated differences in fat fraction between sports and knee structure abnormalities. Results: The area under the receiver operating characteristic (ROC) curve (AUC; maximum 0.79) indicated that IPFP radiomics from fat-only images can differentiate between basketball and swimming athletes. Tendinopathy was identified (AUC = 0.68 ± 0.05) at larger patch sizes. Qualitative radiological assessments of cartilage lesions and bone abnormalities were not distinguished (AUC < 0.57). Fat fraction did not differ across sports or knee structure abnormality (p > 0.49, mean difference < 0.5%). Conclusions: In the absence of inflammatory arthropathy, IPFP radiomics discriminated between sports but not cartilage lesions, tendinopathy, or bone abnormalities, suggesting structural adaptation to sport-specific loading. Abnormal IPFP signal intensity may not present in young athletes without traumatic injury or knee arthroscopy.

Indexed as

BasketballInfrapatellar fat padKnee structure abnormalitiesMRIRadiomics

Identifiers

PMID42239636
PMCPMC13228674

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.