Evidence map›Paper›PMID 42239745›Full record

ArticleCurrent research in microbial sciences2026

Antiviral potential of black tea and blueberry extracts against monkeypox virus by targeting orthopoxvirus surface proteins.

Yi'ou Sha, Yixin Li, Yanchen Liu, Jiannan Chen, Chen Hua, Yangguang Fu, Xinxin Yuan, Yan Yan, Suya Jin, Yitong Li and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current research in microbial sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Yi'ou ShaKey Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), Shanghai Institute of Infectious Disease and Biosecurity, School of Basic Medical Sciences, Shanghai Frontiers Science Center of Pathogenic Microorganisms and Infection, School of Pharmaceutical Sciences, Shanghai Medical College, Fudan University, Shanghai, 200032, China.
Yixin LiKey Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), Shanghai Institute of Infectious Disease and Biosecurity, School of Basic Medical Sciences, Shanghai Frontiers Science Center of Pathogenic Microorganisms and Infection, School of Pharmaceutical Sciences, Shanghai Medical College, Fudan University, Shanghai, 200032, China.
Yanchen LiuNutrition and Health Research Institute, School of Life Science and Technology, Wuhan Polytechnic University, Wuhan, 430048, China.
Jiannan ChenKey Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), Shanghai Institute of Infectious Disease and Biosecurity, School of Basic Medical Sciences, Shanghai Frontiers Science Center of Pathogenic Microorganisms and Infection, School of Pharmaceutical Sciences, Shanghai Medical College, Fudan University, Shanghai, 200032, China.
Chen HuaKey Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), Shanghai Institute of Infectious Disease and Biosecurity, School of Basic Medical Sciences, Shanghai Frontiers Science Center of Pathogenic Microorganisms and Infection, School of Pharmaceutical Sciences, Shanghai Medical College, Fudan University, Shanghai, 200032, China.
Yangguang FuKey Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), Shanghai Institute of Infectious Disease and Biosecurity, School of Basic Medical Sciences, Shanghai Frontiers Science Center of Pathogenic Microorganisms and Infection, School of Pharmaceutical Sciences, Shanghai Medical College, Fudan University, Shanghai, 200032, China.
Xinxin YuanKey Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), Shanghai Institute of Infectious Disease and Biosecurity, School of Basic Medical Sciences, Shanghai Frontiers Science Center of Pathogenic Microorganisms and Infection, School of Pharmaceutical Sciences, Shanghai Medical College, Fudan University, Shanghai, 200032, China.
Yan YanKey Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), Shanghai Institute of Infectious Disease and Biosecurity, School of Basic Medical Sciences, Shanghai Frontiers Science Center of Pathogenic Microorganisms and Infection, School of Pharmaceutical Sciences, Shanghai Medical College, Fudan University, Shanghai, 200032, China.
Suya JinKey Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), Shanghai Institute of Infectious Disease and Biosecurity, School of Basic Medical Sciences, Shanghai Frontiers Science Center of Pathogenic Microorganisms and Infection, School of Pharmaceutical Sciences, Shanghai Medical College, Fudan University, Shanghai, 200032, China.
Yitong LiKey Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), Shanghai Institute of Infectious Disease and Biosecurity, School of Basic Medical Sciences, Shanghai Frontiers Science Center of Pathogenic Microorganisms and Infection, School of Pharmaceutical Sciences, Shanghai Medical College, Fudan University, Shanghai, 200032, China.
Anqi XiaKey Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), Shanghai Institute of Infectious Disease and Biosecurity, School of Basic Medical Sciences, Shanghai Frontiers Science Center of Pathogenic Microorganisms and Infection, School of Pharmaceutical Sciences, Shanghai Medical College, Fudan University, Shanghai, 200032, China.
Qian WangKey Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), Shanghai Institute of Infectious Disease and Biosecurity, School of Basic Medical Sciences, Shanghai Frontiers Science Center of Pathogenic Microorganisms and Infection, School of Pharmaceutical Sciences, Shanghai Medical College, Fudan University, Shanghai, 200032, China.
Qiao WangKey Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), Shanghai Institute of Infectious Disease and Biosecurity, School of Basic Medical Sciences, Shanghai Frontiers Science Center of Pathogenic Microorganisms and Infection, School of Pharmaceutical Sciences, Shanghai Medical College, Fudan University, Shanghai, 200032, China.
Yinghua ChenNutrition and Health Research Institute, School of Life Science and Technology, Wuhan Polytechnic University, Wuhan, 430048, China.
Rong ZhangKey Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), Shanghai Institute of Infectious Disease and Biosecurity, School of Basic Medical Sciences, Shanghai Frontiers Science Center of Pathogenic Microorganisms and Infection, School of Pharmaceutical Sciences, Shanghai Medical College, Fudan University, Shanghai, 200032, China.
Shibo JiangKey Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), Shanghai Institute of Infectious Disease and Biosecurity, School of Basic Medical Sciences, Shanghai Frontiers Science Center of Pathogenic Microorganisms and Infection, School of Pharmaceutical Sciences, Shanghai Medical College, Fudan University, Shanghai, 200032, China.
Jian YingNutrition and Health Research Institute, School of Life Science and Technology, Wuhan Polytechnic University, Wuhan, 430048, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Monkeypox virus (MPXV) outbreaks primarily affect resource-limited regions in Africa, highlighting an urgent need for low-cost, accessible therapeutics. Food-medicine homologous (FMH) substances, which are bioactive food components with medicinal properties, offer a promising therapeutic avenue owing to their low cost, favorable safety, and oral bioavailability. Here, we report that black tea extract (BTE) and blueberry extract (BBE), two representative FMH substances, can inhibit the vaccinia virus (VACV) and MPXV. Mechanistic studies suggest that BTE and BBE act at the post-attachment stage of viral entry by interacting with the orthopoxvirus surface proteins B6R and L1R. In a murine model of VACV infection, both extracts demonstrated modest

Indexed as

Antiviral activityBlack tea extract (BTE)Blueberry extract (BBE)Monkeypox virus (MPXV)Orthopoxvirus

Identifiers

PMID42239745
PMCPMC13226137

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.