Evidence map›Paper›PMID 42240863›Full record

ArticleActa diabetologica2026

HbA1c variability as an independent risk factor for diabetic retinopathy: results from a screening program.

Maria Ida Maiorino, Carlo Gesualdo, Silvia Angelino, Settimio Rossi, Nicole Di Martino, Clemente Iodice, Miriam Longo, Lorenzo Scappaticcio, Giuseppe Bellastella, Francesca Simonelli and 1 more

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Article in Acta diabetologica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Maria Ida Maiorino *Department of Advanced Medical and Surgical Sciences, University of Campania "Luigi Vanvitelli", Piazza Miraglia 2, 80138, Naples, Italy. mariaida.maiorino@unicampania.it.ORCID http://orcid.org/0000-0003-4659-7546
Carlo Gesualdo *Eye Clinic, Multidisciplinary Department of Medical, Surgical and Dental Sciences, University of Campania, "Luigi Vanvitelli", Naples, Italy.ORCID http://orcid.org/0000-0003-4955-7857
Silvia AngelinoPhD Program of Translational Medicine, Department of Advanced Medical and Surgical Sciences, University of Campania "Luigi Vanvitelli", Naples, Italy.ORCID http://orcid.org/0009-0008-1503-6918
Settimio RossiEye Clinic, Multidisciplinary Department of Medical, Surgical and Dental Sciences, University of Campania, "Luigi Vanvitelli", Naples, Italy.ORCID http://orcid.org/0000-0002-8682-6860
Nicole Di MartinoDivision of Endocrinology and Metabolic Diseases, University Hospital, University of Campania "Luigi Vanvitelli", Piazza Miraglia 2, 80138, Naples, Italy.ORCID http://orcid.org/0009-0001-8062-3958
Clemente IodiceEye Clinic, Multidisciplinary Department of Medical, Surgical and Dental Sciences, University of Campania, "Luigi Vanvitelli", Naples, Italy.ORCID http://orcid.org/0000-0003-1688-6646
Miriam LongoDepartment of Advanced Medical and Surgical Sciences, University of Campania "Luigi Vanvitelli", Piazza Miraglia 2, 80138, Naples, Italy.ORCID http://orcid.org/0000-0002-6459-5854
Lorenzo ScappaticcioDepartment of Advanced Medical and Surgical Sciences, University of Campania "Luigi Vanvitelli", Piazza Miraglia 2, 80138, Naples, Italy.ORCID http://orcid.org/0000-0003-2972-9551
Giuseppe BellastellaDepartment of Advanced Medical and Surgical Sciences, University of Campania "Luigi Vanvitelli", Piazza Miraglia 2, 80138, Naples, Italy.ORCID http://orcid.org/0000-0002-4748-321X
Francesca SimonelliEye Clinic, Multidisciplinary Department of Medical, Surgical and Dental Sciences, University of Campania, "Luigi Vanvitelli", Naples, Italy.ORCID http://orcid.org/0000-0001-8520-6769
Katherine EspositoDepartment of Advanced Medical and Surgical Sciences, University of Campania "Luigi Vanvitelli", Piazza Miraglia 2, 80138, Naples, Italy.ORCID http://orcid.org/0000-0002-3652-5154

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo investigate the independent association between long-term glycemic variability, measured as the coefficient of variation (CV) of HbA1c, and the presence of diabetic retinopathy (DR) in a cohort of adults with diabetes within a systematic eye screening program.

methodsThis study screened 379 adults with type 1 and type 2 diabetes. Long-term glycemic variability was calculated as the CV of serial HbA

resultsDR incidence of 12.4%, mostly mild non-proliferative. The median HbA

conclusionsIn conclusion, in a cohort of individuals with both type 1 and type 2 diabetes and a low incidence of DR, long-term glycemic variability, estimated as HbA

Indexed as

Diabetes Mellitus, Type 1Diabetes Mellitus, Type 2Diabetic RetinopathyGlycated HemoglobinAdultAgedBlood GlucoseFemaleHumansIncidenceMaleMass ScreeningMiddle AgedRisk FactorsBlood GlucoseGlycated Hemoglobinhemoglobin A1c protein, humanDiabetic retinopathyGlucose variabilityHbA1c coefficient of variationRetinopathy screeningType 1 diabetesType 2 diabetes

Identifiers

PMID42240863
PMCPMC13469500

What Socratic holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.