SynthesisInternal medicine journal2026
Demographic, perioperative, biochemical and illness-severity predictors of thirst in critically ill patients: a systematic review and meta-analysis.
Synthesis in Internal medicine journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
4 authors.
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Abstract
Thirst is a prevalent and distressing symptom among critically ill and surgical patients, yet its predictors remain poorly characterised. We aimed to quantify the associations between patient demographics, treatment modalities, biochemical markers and illness severity with self-reported thirst in critical settings. We conducted a systematic review and meta-analysis of studies published through April 2025 in PubMed, Embase, Web of Science, Cochrane Library and Ovid MEDLINE. Eligible observational studies in adult intensive care or perioperative cohorts reported associations between thirst and at least one of six factors: sex, anaesthetic technique, mechanical ventilation, blood urea nitrogen (BUN), serum osmolality or Acute Physiology and Chronic Health Evaluation (APACHE-II) score. Data were pooled using DerSimonian-Laird random-effects models to estimate odds ratios (ORs) for dichotomous predictors and weighted or standardised mean differences (WMDs/SMDs) for continuous variables. Heterogeneity was assessed by I
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