ArticlebioRxiv : the preprint server for biology2026
A conserved dimerization element is required for protein kinase activation by
Samuel Botterbusch, Vienna L Huso, Kyler A Weingartner, Gretar Tryggvason, Katherine W Tripp, Rachel Green, Jennifer M Kavran
Abstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
7 authors.
Samuel BotterbuschDepartment of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.ORCID 0000-0002-1593-6069 Vienna L HusoDepartment of Molecular Biology and Genetics, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Kyler A WeingartnerDepartment of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
Gretar TryggvasonDepartment of Mechanical Engineering, Whiting School of Engineering, Johns Hopkins University, Baltimore, MD, USA.
Katherine W TrippDepartment of Biophysics, Krieger School of Arts and Sciences, Johns Hopkins University, Baltimore, MD, USA.
Rachel GreenDepartment of Molecular Biology and Genetics, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Jennifer M KavranDepartment of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.ORCID 0000-0001-9117-5209 Funding
BIOCHEMISTRY, CELLULAR AND MOLECULAR BIOLOGY PROGRAMT32GM007445 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI GREEN, RACHEL · 1985 to 2021
$24.1MPROGRAM IN MOLECULAR BIOPHYSICST32GM008403 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI BARRICK, DOUGLAS E. · 1990 to 2019
$13.5MTRAINING IN AREAS FUNDAMENTAL TO CANCER RESEARCHT32CA009110 · NCI · JOHNS HOPKINS UNIVERSITY · PI MATUNIS, MICHAEL J., WEERARATNA, ASHANI T · 1985 to 2025
$13.1MChimeraX -- Next Generation Visualization and Analysis Software for Multiscale ModelingR01GM129325 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FERRIN, THOMAS E · 2018 to 2025
$5.2MMolecular mechanisms of ribosome pausing and the cellular responseR37GM059425 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI GREEN, RACHEL · 2014 to 2023
$3.5MMolecular mechanisms of ribosome-mediated kinase signalingR35GM156244 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI GREEN, RACHEL · 2025 to 2025
$2.1MMechanistic studies of protein kinasesR35GM156573 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI Jennifer Marie Kavran · 2025 to 2026
$776kNCI NIH HHS T32 CA009110NIGMS NIH HHS R01 GM129325NIGMS NIH HHS R35 GM156244NIGMS NIH HHS R35 GM156573NIGMS NIH HHS R37 GM059425NIGMS NIH HHS T32 GM007445NIGMS NIH HHS T32 GM008403
6 · The paper itselfAbstract
PubMed holds no abstract for this paper.
Indexed as
Biological Sciences – BiochemistryBiophysics and Computational Biologyprotein kinaseprotein-protein interactionssignal transduction
Identifiers
PMID42244635
PMCPMC13232308
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