Evidence map›Paper›PMID 42244704›Full record

ArticlebioRxiv : the preprint server for biology2026

MeCP2 is Necessary in Cerebellar Purkinje Cells for Precise Network Dynamics During Associative Motor Learning.

Jenny Shen, Peter Shen, Julia Lopes Gonçalez, Mikayla Jackson, Likhitha Polepalli, Kruthika Dheeravath, Timothy Li, Abdulla Hamki, Mariam Hamki, Christian Hicks and 3 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jenny ShenDepartment of Neurobiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Peter ShenDepartment of Neurobiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Julia Lopes GonçalezGraduate Program in Behavioral Neuroscience, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Mikayla JacksonDepartment of Neurobiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Likhitha PolepalliDepartment of Neurobiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Kruthika DheeravathDepartment of Neurobiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Timothy LiDepartment of Neurobiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Abdulla HamkiDepartment of Neurobiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Mariam HamkiDepartment of Neurobiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Christian HicksDepartment of Neurobiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Chang LiDepartment of Neurobiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Lucas Pozzo-MillerDepartment of Pediatrics & Human Development, College of Human Medicine, Michigan State University, Grand Rapids, MI 49503, USA.ORCID 0000-0001-6085-5527
Wei LiDepartment of Neurobiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.

Funding

The Pathophysiological Role of Cerebellar Glia in Rett SyndromeR01NS121542 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Wei Li · 2021 to 2026
$1.8M
Defective Thalamic Projections to Dorsal Striatum in Rett SyndromeR21NS097913 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LI, WEI, POZZO-MILLER, LUCAS D · 2017 to 2018
$408k
Dopaminergic Modulation of Astrocytic Function in the CerebellumR21NS108508 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LI, WEI, POZZO-MILLER, LUCAS D · 2018 to 2019
$408k
Impaired Astroglial Glutamate Signaling in Rett SyndromeR21NS120315 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LI, WEI, POZZO-MILLER, LUCAS D · 2020 to 2020
$408k
NINDS NIH HHS R01 NS121542NINDS NIH HHS R21 NS097913NINDS NIH HHS R21 NS108508NINDS NIH HHS R21 NS120315
6 · The paper itself

Abstract

Loss-of-function variants of

Identifiers

PMID42244704
PMCPMC13232184

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.