Evidence map›Paper›PMID 42245334›Full record

SynthesisFrontiers in public health2026

The effects of virtual reality training on cognitive function in older adults: a systematic review and meta-analysis.

Yeqin Lian, Xingyi Li, Changzhou Chen

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yeqin LianSchool of Physical Education, Shanghai University of Sport, Shanghai, China.
Xingyi LiDepartment of Sport and Health, Shinhan University, Dongducheon, Gyeonggi, Republic of Korea.
Changzhou ChenSchool of Physical Education, Shanghai University of Sport, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Virtual reality (VR) has emerged as a promising non-pharmacological approach for supporting cognitive health in older adults. However, the overall magnitude of its effects and the extent to which outcomes vary by cognitive status, intervention duration, and immersion level remain uncertain. Methods: Randomized controlled trials (RCTs) were searched in Web of Science, PubMed, Scopus, Embase, Cochrane Library, and Wanfang Database from database inception to September 24, 2025, without language restrictions. Eligible studies included older adults receiving VR-based training compared with routine rehabilitation, conventional training, no intervention, or non-VR controls. Outcomes were classified as global cognition, TMT-based executive/attention-related performance, and functional mobility. Risk of bias was assessed using the Cochrane RoB 2 tool. Random-effects meta-analyses were conducted using standardized mean differences (SMDs) with 95% confidence intervals (CIs). Subgroup analyses were interpreted as exploratory. Results: Ten RCTs involving 749 participants were included. VR-based training significantly improved global cognition (SMD = 0.49, 95% CI: 0.25-0.73, Conclusion: VR-based training may improve global cognition in older adults and may also benefit functional mobility. Evidence for TMT-based executive/attention-related performance remains preliminary. Current evidence is insufficient to support firm conclusions regarding optimal intervention duration, preferred immersion level, or subgroup superiority. Larger, well-designed RCTs with standardized outcome classification and longer follow-up are needed. Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/view/CRD420251208123, Identifier: CRD420251208123.

Indexed as

CognitionVirtual RealityAgedCognitive EnhancementCognitive TrainingHumansRandomized Controlled Trials as Topiccognitionexecutive functionmeta-analysisolder adultsvirtual reality

Identifiers

PMID42245334
PMCPMC13229813

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.