Evidence map›Paper›PMID 42246276›Full record

ArticleGut microbes2026

Genetic variants of the transporter SLC22A4 affect the abundance and survival of

Samah Chouaibi, Veronica Fertitta, Silvia Porreca, Leila Njim, Antonella Carcagnì, Gabriele Toietta, Gianluca Canettieri, Khadija Zouari, Maha Mastouri, Yosr Kadri and 1 more

Abstract read
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In one paragraph

Article in Gut microbes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Samah ChouaibiDepartment of Translational Medicine and Surgery, Faculty of Medicine, Università Cattolica del Sacro Cuore, Rome, Italy.
Veronica FertittaDepartment of Translational Medicine and Surgery, Faculty of Medicine, Università Cattolica del Sacro Cuore, Rome, Italy.
Silvia PorrecaDepartment of Translational Medicine and Surgery, Faculty of Medicine, Università Cattolica del Sacro Cuore, Rome, Italy.
Leila NjimDepartment of Pathological Anatomy and Cytology, Fattouma Bourguiba University Hospital, Monastir, Tunisia.
Antonella CarcagnìFacility of Epidemiology and Biostatistics-Gemelli Generator, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Gabriele ToiettaTumor Immunology and Immunotherapy Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
Gianluca CanettieriDepartment of Molecular Medicine, Sapienza University of Rome, Rome, Italy.
Khadija ZouariColorectal Diseases Research Unit, Faculty of Medicine, University of Monastir, Monastir, Tunisia.
Maha MastouriLaboratory of Transmissible Diseases and Biologically Active Substances LR99ES27, Faculty of Pharmacy, University of Monastir, Monastir, Tunisia.
Yosr KadriLaboratory of Transmissible Diseases and Biologically Active Substances LR99ES27, Faculty of Pharmacy, University of Monastir, Monastir, Tunisia.
Giovambattista PaniDepartment of Translational Medicine and Surgery, Faculty of Medicine, Università Cattolica del Sacro Cuore, Rome, Italy.ORCID 0000-0001-7133-8728

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The intestinal microbiota influences colorectal cancer (CRC) development, but its interactions with the host's genetic profile during tumorigenesis are poorly understood. We quantified the CRC-associated pathobiont

Indexed as

Colorectal NeoplasmsFusobacterium InfectionsFusobacterium nucleatumOrganic Cation Transport ProteinsAgedEscherichia coliFemaleGastrointestinal MicrobiomeGenetic VariationHumansMaleMiddle AgedNeoplastic Stem CellsSymportersOrganic Cation Transport ProteinsSLC22A4 protein, humanSymporterscancer stem cellsColorectal cancerFusobacterium nucleatumgenetic variantsinnate immunitymicrobiotaOCTN1

Identifiers

PMID42246276
PMCPMC13245087

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.