ReviewCell transplantation
Stem cell-based approaches for alopecia: A narrative review of current and emerging treatment strategies.
Review in Cell transplantation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The natural cycle of hair growth and shedding is continuous. However, an abnormal rate of hair regrowth can signal alopecia, a condition characterized by excessive hair loss and thinning. Alopecia is a common dermatological concern globally, affecting individuals across all ages and sexes, often resulting in psychological distress and diminished quality of life. Despite the availability of various current therapy options such as minoxidil, finasteride, JAK inhibitors, low-level laser, and hair transplantation, these approaches are often limited by variable efficacy or side effects. Consequently, there is growing research interest in regenerative therapies using stem cells as a promising avenue to overcome these shortcomings. Stem cells, characterized by their ability to self-renew and differentiate into multiple cell types, offer the potential to promote hair follicle regeneration. Among the different stem cell types under investigation, hair follicle stem cells (HFSCs), mesenchymal stem cells (MSCs), and induced pluripotent stem cells (iPSCs) have attracted attention due to their regenerative capabilities and immunomodulatory properties. This narrative review explores the underlying causes of alopecia, current and emerging therapies, particularly emphasizing the therapeutic potential of stem cells and their specialized roles in promoting a supportive environment for the hair follicle and scalp. It also examines ongoing clinical and preclinical studies involving stem cell-based therapies for hair loss, aiming to assess their feasibility as future clinical solutions for alopecia.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.