ArticleChemistry & biodiversity2026
Phytochemical Profile and Insecticidal Potential of Two Halophytes, Atriplex halimus and Suaeda fruticosa, Against Tribolium confusum: In Vitro and In Silico Approaches.
Article in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
This study aimed to investigate the phytochemical profile and evaluate the in vitro and in silico insecticidal activities of methanolic extracts from two halophytes, Atriplex halimus (A. halimus) and Suaeda fruticosa (S. fruticosa). The investigations included phytochemical screening, determination of total phenolic, flavonoid, and tannin contents, as well as compound identification by high-performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight mass spectrometry (HPLC-ESI-QTOF-MS). The insecticidal activity was assessed through direct-contact bioassays against adults of Tribolium confusum. In addition, a molecular docking study was performed targeting the acetylcholinesterase enzyme (AChE). Phytochemical screening revealed the presence of several bioactive compounds in both plant extracts. A. halimus showed the highest flavonoid content, whereas S. fruticosa exhibited the highest levels of total phenolics and tannins, corresponding to superior insecticidal effect, as evidenced by its lower lethal concentration 50% (LC
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