ArticleActa paediatrica (Oslo, Norway : 1992)2026
Metabolic Risk Factors Are Associated With Weight Status Change Over Four Years in Children Aged 4-6 Years With Obesity.
Article in Acta paediatrica (Oslo, Norway : 1992), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Obesity in Preschool Children Should Be Taken Seriously.Acta paediatrica (Oslo, Norway : 1992) · 2026Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
aimIt is unclear how early childhood obesity treatment affects metabolic risk. This study assessed long-term metabolic health in children with obesity aged 4-6 years and examined associations with weight status.
methodsThis prospective cohort study pooled data from the Sweden-based More and Less randomized controlled trial, which compared a parent support program with standard care in 2012-2016. Children met the International Obesity Task Force (IOTF) criteria for obesity. Anthropometrics and metabolic risk factors were collected at baseline, 12 and 48 months. Associations between metabolic markers and weight status were examined using linear mixed models.
resultsData from 106/177 (60%) children, mean age at baseline 5.3 years, were analysed. At baseline, 33/90 (36.6%) had elevated metabolic risk markers. At 48 months, one unit of body mass index standard deviation score (BMI SDS) was associated with higher glycosylated haemoglobin (HbA1c IFCC) (0.99 mmol/mol), higher fasting insulin (2.72 mIU/L) and lower high-density lipoprotein (HDL) (-0.16 mmol/L or -6.2 mg/dL). A BMI SDS reduction ≥ 0.25 was associated with lower HbA1c and triglycerides at 12 months, and a reduction ≥ 0.5 with lower total cholesterol at 48 months.
conclusionImproved weight status may reverse metabolic disturbances present in early childhood.
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Registered trials
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