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ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2026

Health-related quality of life and lifetime QALY loss among Indigenous Australians with chronic conditions: an age-stratified analysis.

Rezwanul Haque, Annika Luebbe, Matthew McGrail, Bushra Farah Nasir, Khorshed Alam, Katharine Wallis, Floyd Leedie, Srinivas Kondalsamy-Chennakesavan

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Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Rezwanul HaqueToowoomba Regional Clinical Unit, Medical School, Faculty of Health, Medicine and Behavioural Sciences, The University of Queensland, Toowoomba, QLD, 4350, Australia. r.haque@uq.edu.au.
Annika LuebbeToowoomba Regional Clinical Unit, Medical School, Faculty of Health, Medicine and Behavioural Sciences, The University of Queensland, Toowoomba, QLD, 4350, Australia.
Matthew McGrailRockhampton Regional Clinical Unit, Medical School, Faculty of Health, Medicine and Behavioural Sciences, The University of Queensland, Rockhampton, QLD, 4700, Australia.
Bushra Farah NasirToowoomba Regional Clinical Unit, Medical School, Faculty of Health, Medicine and Behavioural Sciences, The University of Queensland, Toowoomba, QLD, 4350, Australia.
Khorshed AlamSchool of Business, Law, Humanities and Pathways and Centre for Health Research, University of Southern Queensland, Toowoomba, QLD, 4350, Australia.
Katharine WallisGeneral Practice Clinical Unit, Medical School, The University of Queensland, Brisbane, QLD, 4006, Australia.
Floyd LeedieGoondir Health Services, Dalby, QLD, 4405, Australia.
Srinivas Kondalsamy-ChennakesavanToowoomba Regional Clinical Unit, Medical School, Faculty of Health, Medicine and Behavioural Sciences, The University of Queensland, Toowoomba, QLD, 4350, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIndigenous Australians in rural and remote areas experience substantial health-related quality of life (HRQoL) impacts alongside persistent healthcare access barriers. Community-led virtual primary care services offer an innovative approach to improving access to health care services for Indigenous Australians in rural and remote areas.

objectiveTo examine age-stratified HRQoL patterns and estimate the lifetime quality-adjusted life year (QALY) loss among Indigenous Australians with chronic conditions enrolled in a rural virtual primary care service.

methodsWe conducted a cross-sectional analysis of 75 Indigenous adults residing in rural Queensland. HRQoL was measured using the EQ-5D-5L instrument. Lifetime QALY loss was calculated using Queensland Indigenous life tables and population norms, with sensitivity analyses using Australian norms and varying discount rates.

resultsOverall mean utility was 0.775 (SD = 0.246). Age-stratified analysis revealed significant heterogeneity, with three age groups (18-54, 55-64, 65-74 years) demonstrating lower HRQoL than Queensland norms. The 55-64 age group experienced poorest HRQoL (utility = 0.701, SD = 0.287) and highest projected lifetime QALY loss (4.44 QALYs undiscounted; 2.63 with 5% discount). In contrast, participants aged 75 years and above exceeded population norms (utility = 0.872 vs. 0.863). Chronic disease burden was associated with HRQoL decline in adults aged 18-64 years, while physical activity was associated with higher HRQoL in those aged 65 years and over.

conclusionsIndigenous Australians aged 55-64 years represent a critical priority for virtual primary care interventions. Targeted support strategies for this 'at-risk' age group are essential to address substantial lifetime health burdens and improve long-term outcomes within remote delivery models.

Indexed as

Quality-Adjusted Life YearsQuality of LifeAdolescentAdultAgedAge FactorsAustraliaChronic DiseaseCross-Sectional StudiesFemaleHumansMaleMiddle AgedQueenslandRural PopulationYoung AdultChronic diseaseEQ-5D-5LHealth-related quality of lifeHealth utilityIndigenous healthQuality adjusted life years (QALY)

Identifiers

PMID42250030
PMCPMC13242483

What Socratic holds

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.