ArticleContemporary clinical trials2026
Testing community-based strategies to increase hypertension screening in Nigeria: a protocol for an effectiveness-implementation hybrid type III cluster-randomized trial.
Article in Contemporary clinical trials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06659900 (Community Vital Signs), which is not on this map. Not yet cited in PubMed.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Community Vital Signs (CVS): An Integrated Community-Based Approach to Identify Undiagnosed Hypertension in Nigeria
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14 authors.
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Abstract
backgroundHypertension is a major risk factor for cardiovascular disease and stroke, with a growing burden in Nigeria. Limited access to blood pressure (BP) screenings, low awareness, and barriers to healthcare drive low diagnosis rates. Community-based screenings for other conditions have been successful and could improve diagnosis and care linkage. This study evaluates the effectiveness of a community-based screening and referral intervention to increase hypertension detection and facilitate connections to healthcare.
methodsThis cluster-randomized effectiveness-implementation hybrid type III trial in Nigeria tests the implementation and effectiveness of a community-based BP screening intervention. There are two arms: 1). Core: community screenings supported by mobile health technology with referral to a healthcare facility for participants with at least one elevated BP reading, and 2.) Core+ (enhanced): additional support from community health advisors to help participants link to healthcare facilities. Participants with elevated BP will be informed about medication vouchers if diagnosed with hypertension and prescribed medication. Community gathering sites hosting screenings leverage local engagement structures. The study will assess the proportion of individuals identified to have elevated BP, rates of linkage to healthcare facilities, and factors influencing intervention uptake and sustainability. DISCUSSION: To address gaps in hypertension detection and management utilizing community-based strategies, findings will provide insights into the feasibility and effectiveness of implementing a scalable, community-driven approach to hypertension screening and linkages to healthcare in Nigeria. If successful, this model could be adapted to other resource-limited settings in the United States and globally to improve detection and reduce hypertension-related complications. NAME OF REGISTRY: CLINICALTRIALS.GOV: Trial Registration NCT06659900. Registered 26 October 2024, prospectively registered. https://clinicaltrials.gov/study/NCT06659900?id=NCT06659900&rank=1.
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