ArticleAnalytical chemistry2026
A Color-Tuning Bioluminescent Sensor (AmyLuc) for Real-Time Monitoring of Intracellular pH Dynamics in Cancer Cells.
Article in Analytical chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
2 citing papers in PubMed.
- Mitochondria related gene signature serves as prognosis prediction and risk stratification of cholangiocarcinoma.Translational cancer research · 2026Article
- Lactate-dependent regulation of ferroptosis: redox homeostasis, lactylation, and translational perspectives.Apoptosis : an international journal on programmed cell death · 2026Review
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Authors and funding
7 authors.
Funding
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Abstract
Cancer cells show increased glucose uptake and lactate secretion due to mitochondrial respiratory dysfunction and hypoxia, leading to extracellular acidification of the tumor microenvironment (TME) and intracellular alkalinization. This metabolic reprogramming promotes malignant phenotypes, including enhanced invasion, metastasis, multidrug resistance, and immune evasion. Therefore, real-time monitoring of intra- and extracellular pH dynamics is essential to understand tumor progression and to evaluate therapeutic strategies. Here, we report the use of a pH-sensitive bioluminescent color-tuning biosensor, derived from the firefly
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Registered trials
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