Trial reportFrontiers in nutrition2026
Safety and tolerability of Ashwagandha (
Trial report in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- The Clinical Implications of Ashwagandha (Nutrients · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and aim: Ashwagandha, adaptogenic herb traditionally used to enhance resilience to stress and promote overall well-being. Although its safety at conventional doses is well established, evidence regarding the safety of higher doses in healthy adults remains limited. The present study aimed to evaluate the safety and tolerability of Ashwagandha root extract (ARE) administered at a dose of 2000 mg/day in healthy adults over 12 weeks. Methods: This was a prospective, single-arm, non-comparative clinical study conducted in healthy adults aged 18-65 years. Participants received ARE 500 mg capsules (total daily dose of 2000 mg) orally for 12 weeks. Primary safety outcomes included laboratory evaluations of renal, hepatic, and thyroid parameters. Secondary safety outcomes included clinical assessment of adverse events and changes in quality of life assessed using the SF-36 questionnaire. Results: Over 12 weeks, minor changes ( Conclusion: High-dose Ashwagandha root extract (2000 mg/day) was well tolerated and demonstrated a favourable safety profile in healthy adults over 12 weeks. Trial registration: https://ctri.nic.in/Clinicaltrials/pmaindet2.php?EncHid=ODE3NTk=&Enc=&userName=, Identifier (CTRI/2023/04/051607).
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.