ArticleRadiology case reports2026
Semilobar holoprosencephaly associated with maternal diabetes in a toddler: A case report.
Article in Radiology case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Phenotypic discordance in semilobar holoprosencephaly: a case report of total arhinia and median clefting linked to gestational diabetes.Annals of medicine and surgery (2012) · 2026Article
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3 authors.
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Abstract
Holoprosencephaly is a rare congenital malformation of the forebrain caused by incomplete division of the prosencephalon during early embryonic development, and semilobar holoprosencephaly represents the intermediate form of the spectrum. We report the case of a 3-year-old child presenting with developmental delay, seizures, feeding difficulties, and midline facial abnormalities. The child was born to a mother with poorly controlled maternal diabetes mellitus. The MRI scan of the brain showed partial fusion of the frontal lobes, incomplete separation of the hemispheres of the cerebrum, presence of a single ventricular cavity, partial fusion of the thalami, and lack of the septum pellucidum. These clinical signs suggested semilobar holoprosencephaly. This case underlines the importance of neuroimaging in evaluating children with developmental delay and neurological symptoms, and early recognition of such malformations may contribute to better clinical follow-up and family guidance.
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