ArticleAnnals of medicine and surgery (2012)2026
The influence of unhealthy lifestyle on semen quality: results from a cross-sectional study and Mendelian randomization analysis.
Article in Annals of medicine and surgery (2012), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and aims: Unhealthy lifestyle may influence semen quality. This research aimed to investigate the association of unhealthy lifestyle with the risk of low semen quality and further to examine the causal relationship by Mendelian randomization (MR) method. Methods: The association of six unhealthy lifestyle habits (smoking, alcohol consumption, coffee consumption, sedentary behavior, obesity, and sleep disturbance) with semen quality was assessed using binary logistic regression analysis including 508 participants. A two-sample MR analysis for seven unhealthy lifestyle habits (smoking, alcohol consumption, caffeine consumption, cannabis consumption, sedentary behavior, obesity, and sleep disturbance) and semen quality was conducted. The principal analysis employed the inverse-variance-weighted (IVW) approach. The MR-pleiotropy residual sum and outlier (MR-PRESSO) tests and MR-Egger regression were implemented to evaluate horizontal pleiotropy. Sensitivity analyses were performed with Cochran's Results: During the cross-sectional study, smoking, heavy alcohol and coffee consumption, and sedentary behavior were found to be significantly correlated with an elevated prevalence of low semen quality in the two models ( Conclusion: Our cross-sectional study indicated that smoking, heavy alcohol and coffee consumption, and sedentary behavior were significantly correlated with low semen quality. The MR study supported a causal association between smoking/alcohol consumption/caffeine consumption/cannabis use/sedentary behavior and low semen quality.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.