Evidence map›Paper›PMID 42254259›Full record

ArticleAnnals of medicine and surgery (2012)2026

Meta-analysis and systematic review: efficacy of probiotics in combination with standard therapies for rotavirus enteritis.

Xiang Gao, Hui Zhang, Yangyang Yu, Jia Chen, Yuanming Qu

Abstract read
In one paragraph

Article in Annals of medicine and surgery (2012), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xiang GaoClinical College of Traditional Chinese Medicine, Inner Mongolia Medical University, Hohhot, China.
Hui ZhangClinical College of Traditional Chinese Medicine, Inner Mongolia Medical University, Hohhot, China.
Yangyang YuClinical College of Traditional Chinese Medicine, Inner Mongolia Medical University, Hohhot, China.
Jia ChenDepartment of Proctology, Inner Mongolia Hospital of Traditional Chinese Medicine, Hohhot, China.
Yuanming QuDepartment of Proctology, Inner Mongolia Hospital of Traditional Chinese Medicine, Hohhot, China.ORCID https://orcid.org/0009-0004-4258-9770

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Rotavirus enteritis is the main cause of hospitalization and death in patients with diarrhea. There is no specific drug. Vaccine prevention is effective, but the oral route has safety concerns in developing countries. A safe and effective treatment is urgently needed. Objective: To systematically evaluate the clinical analysis of conventional therapy combined with probiotics in patients with rotavirus enteritis. Materials and methods: We retrieved a total of 14 randomized controlled trials (RCTs) involving 1709 patients from multiple databases. Results: Results showed that probiotics significantly shortened recovery times for defecation frequency [mean difference (MD) = 1.18, 95% confidence interval (CI): 0.76-1.60, Conclusion: Probiotics, by regulating gut microbiota and enhancing mucosal immunity, offer a safe and effective adjunct to conventional therapy for rotavirus enteritis.

Indexed as

efficacy evaluationenteritismeta-analysisprobioticsrotavirus

Identifiers

PMID42254259
PMCPMC13236226

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.