ArticleFrontiers in medicine2026
Beyond the diagnostic threshold: paradigm shift in laboratory medicine from passive reaction to predictive capability.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
4 authors.
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Abstract
Conventional laboratory medicine, which relies on diagnostic thresholds, operates within a reactive framework that is inherently constrained by its retrospective and static nature. This perspective article scrutinizes the paradigm shift in the field from a responsive to a predictive discipline. The transition is centered on integrating multi-omics data, continuous biosensing, and artificial intelligence to build predictive systems capable of early risk identification and individualized health guidance. The perspective article further investigates the conceptual underpinnings, implementation pathways, and related challenges-spanning technical, ethical, and health-system dimensions-of this evolving paradigm. This transformation not only redefines the scope of laboratory medicine but also positions it as a foundational component within precision medicine and prevention-focused public health frameworks.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.