Evidence map›Paper›PMID 42254738›Full record

ArticleFrontiers in psychiatry2026

ESMR: a process framework for calibration dynamics across psychosomatic and psychiatric phenomena.

Daisuke Yamashita

Abstract read
In one paragraph

Article in Frontiers in psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Daisuke YamashitaDepartment of Pediatrics and Child Health, Kurume University School of Medicine, Kurume, Fukuoka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The brain can be modeled as a generative system that predicts bodily and environmental input and reduces mismatch through updating and action. From this perspective, stress is treated not as prediction error per se, but as a condition in which mismatch persists without sufficient recalibration. Health is therefore defined not as the absence of symptoms, but as the preservation of recalibrability, whereas psychopathology is conceptualized as the progressive fixation of recalibration failure. This paper proposes ESMR as a four-layer, two-timescale process framework for comparing psychosomatic conditions, psychiatric disorders, and psychosis-level phenomena in terms of partially shared failures of recalibration rather than as a single disease continuum. ESMR distinguishes E (Embodied Constraints), S (Salience Calibration), M (Metacognitive Model Revision), and R (Reality-Grounding Interface) across learning (L) and development (D). Development is treated not merely as slower accumulation of prior learning, but as change in the biological, representational, and self-regulatory architecture that alters both what forms of recalibration are possible and the background conditions under which learning can be taken up. A central distinction is that M concerns whether corrective information can be converted into updating, whereas R concerns whether already understood correction can be adopted as self-relevant reality under embodied, practical, and interpersonal constraints, with downstream transfer treated as a consequence rather than part of the R core. The framework predicts layer-specific cross-signatures rather than a single undifferentiated burden effect and outlines a staged empirical program using framing, disconfirmation, reality-grounding, and embodied/interoceptive tasks. ESMR is offered as a revisable, clinically oriented intermediate framework rather than a completed computational model.

Indexed as

active inferenceESMRmetacognitionpsychological therapypsychosomatic medicinereality groundingrecalibrabilitytransdiagnostic psychopathology

Identifiers

PMID42254738
PMCPMC13234513

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.