Evidence mapPaperPMID 42255285Full record

ArticleFrontiers in digital health2026

A mobile intervention to reduce pain and improve health-III: protocol for a remotely delivered randomized controlled trial of physical activity for pain management in older adults with obesity and knee or hip osteoarthritis.

Jason Fanning, Deja O Dobson, Sherri A Ford, Megan Bennett, Iris Leng, Anna C Martin, James Merritt, Fancis J Keefe, W Jack Rejeski, Amber K Brooks

Abstract read
In one paragraph

Article in Frontiers in digital health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jason FanningDepartment of Health and Exercise Science, Wake Forest University, Winston Salem, NC, United States.
Deja O DobsonDepartment of Health and Exercise Science, Wake Forest University, Winston Salem, NC, United States.
Sherri A FordDepartment of Health and Exercise Science, Wake Forest University, Winston Salem, NC, United States.
Megan BennettDepartment of Health and Exercise Science, Wake Forest University, Winston Salem, NC, United States.
Iris LengBiostatistics and Data Science, Wake Forest University School of Medicine, Winston Salem, NC, United States.
Anna C MartinDepartment of Health and Exercise Science, Wake Forest University, Winston Salem, NC, United States.
James MerrittDepartment of Health and Exercise Science, Wake Forest University, Winston Salem, NC, United States.
Fancis J KeefeDepartment of Psychiatry and Behavioral Science, Duke University, Durham, NC, United States.
W Jack RejeskiDepartment of Health and Exercise Science, Wake Forest University, Winston Salem, NC, United States.
Amber K BrooksDepartment of Anesthesiology, Wake Forest University School of Medicine, Winston Salem, NC, United States.

Funding

A Mobile Health Behavior Intervention to Reduce Pain and Improve Health-III (MORPH-III)R01AG082777 · WAKE FOREST UNIVERSITY · 2025 to 2025
$1.2M
NIA NIH HHS R01 AG082777
6 · The paper itself

Abstract

As many as three in four older adults live with chronic pain, and osteoarthritis is a leading cause of chronic pain in older adults. Knee and hip osteoarthritis being the most common forms of the condition. Osteoarthritis symptoms are worsened by low levels of physical activity, excess sustained sedentary time, weight gain, and social isolation, ultimately impairing quality of life. Data from several pilot trials have demonstrated the feasibility, acceptability, and potential benefit of a unique remote group-mediated behavioral intervention rooted in social cognitive and self-determination theories that targets three domains of behavior change: (1) dietary behavior change with a focus on weight loss via caloric restriction alongside diet quality, satiety, and reduced inflammation, (2) increased physical activity, and (3) decreased sitting via the accumulation of steps in frequent bouts throughout the day (i.e., daylong movement). Herein we describe the protocol for a Stage-II parallel randomized controlled trial examining the efficacy of 6 months of a remotely delivered group-mediated daylong movement and weight loss intervention in older adults with obesity and chronic knee or hip osteoarthritic pain. Outcomes of interest include daily steps (primary outcome) and pain interference, body weight, and physical function (secondary outcomes). We will also explore intervention effects on long-term behavior change over 12 months following the intervention and whether changes in steps, body weight, pain catastrophizing, or pain self-efficacy mediate intervention effects on pain interference, if present. Low-active older adults (

Indexed as

behavior changeolder adultphysical activitysedentary behaviortechnology

Identifiers

PMID42255285
PMCPMC13234624

What Socratic holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.